Applications

A landmark achievement in the reduction of animal testing, MatTek's Skin Irritation Test is OECD accepted as a replacement for in vivo irritation testing.

Examine changes in extracellular matrix (ECM) gene and protein expression and histological structure to determine the anti-aging efficacy of cosmetic ingredients or final formulation. EpiDermFT is available from a range of adult donors. METHODS EpiDermFT tissues (Figure 1) are equilibrated... Read More

The MelanoDerm Skin Brightening Assay provides an early screening tool to increase the chances of a formulation's success in clinical trials. 

The EpiDerm Skin Corrosion Test reliably identifies corrosive chemicals for the classification of skin corrosion hazard according to OECD.

The Model The Psoriasis tissue model is cultured using normal human epidermal keratinocytes and psoriatic fibroblasts harvested from psoriatic skin tissue specimens. The cells are cultured on specially prepared tissue culture inserts using serum free medium to form a multilayered,... Read More