Applications

November 19, 2015

Genotoxicity

Use MatTek’s EpiDerm model with the COMET or Micronucleus assays to assess genotoxic potential of chemicals or other formulations.   The Model MatTek’s patented EpiDerm™ System consists of normal, human-derived epidermal keratinocytes (NHEK) which have been cultured to form a... Read More
November 19, 2015

Phototoxicity (OECD TG 498)

Phototoxicity (OECD TG 498)
The EpiDerm Phototoxicity Assay measures acute toxic response after exposure of skin to chemicals and subsequent exposure to light.
November 19, 2015

Pigmentation Studies

The Model MatTek’s MelanoDerm™ System consists of normal, human-derived epidermal keratinocytes (NHEK) and melanocytes (NHM) which have been cultured to form a multilayered, highly differentiated model of the human epidermis. The NHM within co-cultures undergo spontaneous melanogenesis leading to tissues... Read More
November 19, 2015

Dermal Drug Delivery

The Model MatTek’s patented EpiDerm™ System consists of normal, human-derived epidermal keratinocytes (NHEK) which have been cultured to form a multilayered, highly differentiated model of the human epidermis. These “ready-to-use” tissues, also known generically as normal human 3D tissues, are... Read More
November 19, 2015

Skin Hydration

Measure the electrical impedance of EpiDermFT to assess the efficacy of topically applied moisturizers including creams, gels and lotions.