Skin Brightening

The MelanoDerm Skin Brightening Assay provides invaluable in vitro data as an early screening tool for raw materials to reduce costs and increase the chances of a formulation’s success prior to clinical trials. Cosmetics manufacturers continually develop safer and more effective skin brightening products for their customers struggling with melasma and post-inflammatory hyperpigmentation. Evaluate the efficacy of cosmetic and/or pharmaceutical skin care formulations that are used to combat skin pigmentation disorders with MelanoDerm.

MatTek offers MelanoDerm Skin Brightening/melanogenesis assay as a non-GLP service.

Protocol

Test Model	MelanoDerm
Replicates	N=8 tissues per test condition
Exposure Conditions	3 treatments/week for 2 weeks with 25µl of test material and controls
Assay Controls	2% Kojic Acid (positive control), DI H₂O (negative control)
Endpoints	Macroscopic analysis, Histological analysis, Quantitative Melanin Assay
Data Delivery	Histological images and analysis, Melanin Assay Analysis, Macroscopic photos skin brightening potential