Reference Libraries

National and international regulations require that chemicals must be properly classified, labeled, packaged, and transported based on their ability to damage or destroy tissue, e.g., skin. Traditional rabbit tests for assessing skin irritation or corrosion are based on the methods... Read More

In 1996 and 1997, ECVAM supported a formal validation study on in vitro methods for predicting skin corrosivity. Two of the in vitro tests included in the study employed human skin models, the Skin ZK1350 and EPISKIN™ models. In the... Read More

The purpose of this study, conducted by scientists at Unilever’s Safety and Environmental Assurance Centre, was to assess the in-house performance of the EpiDerm and EPISKIN corrosivity tests using materials of known corrosive potential (six corrosives and six non-corrosives), as... Read More

National and international regulations require that chemicals must be properly classified, labeled, packaged, and transported based on their ability to damage or destroy tissue, e.g., skin. Traditionally, skin corrosion assessments were based on tests involving topical application of test substances... Read More