Reference Libraries

December 11, 2015

HUMAN SKIN EQUIVALENT: A RELIABLE IN VITRO MODEL FOR CARCINOGENIC EXPERIMENTS.

EpiDermFT (MatTek Co., MA) is an in vitro model for human skin derived from keratinocytes of human neonatal foreskin. The epidermal component is cultured to form a highly differentiated model of metabolically and mitotically active cells that are arranged analogous... Read More

December 11, 2015

DETECTING REACTIVE OXYGEN SPECIES IN SKIN USING TWO-PHOTON FLUORESCENCE IMAGING MICROSCOPY.

Reactive oxygen species (ROS) contribute to skin photodamage including photoaging, immunomodulation, actinic keratosis and skin cancers. Because these highly-reactive derivatives of molecular oxygen are extremely short-lived and essentially non-emissive, they are difficult to detect directly. In addition, until recently with... Read More

December 11, 2015

RECONSTRUCTED HUMAN SKIN MODEL TO STUDY MELANOMA AT DIFFERENT STAGES OF PROGRESSION.

This study by scientists at MatTek Corp. demonstrated that MatTek’s EpiDerm-FT in vitro human full-thickness skin tissue equivalent can be co-cultured with melanocytes at different stages of malignancy to produce three dimensional, serum-free tissue culture models that can be used... Read More

December 11, 2015

INFLUENCE OF SOYBEAN SYMBIOSOME EXTRACT ON UV-INDUCED SKIN FREE-RADICAL BIOCHEMISTRY.

This study by researchers at Arch Personal Care Products, Arch Chemicals, Bioinnovation Laboratories, Inc., and Dermscan Group demonstrated how MatTek’s EpiDermFT full-thickness in vitro human skin tissue equivalent can be used to measure the ability of a topically-applied formulation to... Read More

December 11, 2015

UPREGULATION OF SOX9 INHIBITS THE GROWTH OF HUMAN AND MOUSE MELANOMAS AND RESTORES THEIR SENSITIVITY TO RETINOIC ACID.

This study by researchers at the National Cancer Institute (NIH) demonstrated that MatTek’s Melanoma in vitro human skin tissue equivalent can be used to investigate both the efficacy and cytotoxicity of potential malignant melanoma treatments. Treatments for primary and metastatic... Read More

Reference Libraries

HUMAN SKIN EQUIVALENT: A RELIABLE IN VITRO MODEL FOR CARCINOGENIC EXPERIMENTS.

DETECTING REACTIVE OXYGEN SPECIES IN SKIN USING TWO-PHOTON FLUORESCENCE IMAGING MICROSCOPY.

RECONSTRUCTED HUMAN SKIN MODEL TO STUDY MELANOMA AT DIFFERENT STAGES OF PROGRESSION.

INFLUENCE OF SOYBEAN SYMBIOSOME EXTRACT ON UV-INDUCED SKIN FREE-RADICAL BIOCHEMISTRY.

UPREGULATION OF SOX9 INHIBITS THE GROWTH OF HUMAN AND MOUSE MELANOMAS AND RESTORES THEIR SENSITIVITY TO RETINOIC ACID.

Get the latest