Reference Libraries

December 11, 2015

UVB IRRADIATION OF AN ORGANOTYPIC SKIN MODEL, EPIDERM, RESULTS IN SIGNIFICANT RELEASE OF CYTOKINES.

Ultraviolet light, especially UVB (290-320 nm), is believed to be responsible for most of the immediate and long term effects of excessive exposure to sunlight. In many cases, the initial stages of these UV induced changes are the release of... Read More

December 11, 2015

Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to Rhinovirus

Objectives: Human airway epithelial cells are the principal target of human rhinovirus (HRV), a common cold pathogen that triggers the majority of asthma exacerbations. The objectives of this study were 1) to evaluate an in vitro air liquid interface cultured... Read More

December 11, 2015

ROSCOVITINE INHIBITS DIFFERENTIATION AND INVASION IN A THREE-DIMENSIONAL SKIN RECONSTRUCTION MODEL OF METASTATIC MELANOMA.

This study by researchers at the H. Lee Moffitt Cancer Center and Research Institute, and the Mitchell Cancer Institute (Univ. of South Alabama) demonstrated that the MatTek 3-D Melanoma Tissue Model can be used to investigate the therapeutic potential of... Read More

December 11, 2015

FORMULATION DEVELOPMENT OF siRNAs FOR DRUG DELIVERY: A NEW THERAPEUTIC APPROACH FOR PANDEMIC INFLUENZA.

This study by scientists at Nastech Pharmaceuticals demonstrated how MatTek’s EpiAirway human tracheal/bronchial tissue equivalent can be used to identify lipids that facilitate siRNA uptake in lung tissue. This was part of a program to develop siRNA-based therapeutics designed for... Read More

December 11, 2015

A SMALL-MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL.

This study by researchers at the H. Lee Moffitt Cancer Center and Research Institute demonstrated how MatTek’s Melanoma in vitro human skin tissue equivalent can be used to investigate both the efficacy of potential melanoma therapeutic agents and their potential... Read More

Reference Libraries

UVB IRRADIATION OF AN ORGANOTYPIC SKIN MODEL, EPIDERM, RESULTS IN SIGNIFICANT RELEASE OF CYTOKINES.

Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to Rhinovirus

ROSCOVITINE INHIBITS DIFFERENTIATION AND INVASION IN A THREE-DIMENSIONAL SKIN RECONSTRUCTION MODEL OF METASTATIC MELANOMA.

FORMULATION DEVELOPMENT OF siRNAs FOR DRUG DELIVERY: A NEW THERAPEUTIC APPROACH FOR PANDEMIC INFLUENZA.

A SMALL-MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL.

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UVB IRRADIATION OF AN ORGANOTYPIC SKIN MODEL, EPIDERM, RESULTS IN SIGNIFICANT RELEASE OF CYTOKINES.