Reference Libraries

December 11, 2015

FLAVONOIDS DIFFERENTIALLY REGULATE IFN-GAMMA-INDUCED ICAM-1 EXPRESSION IN HUMAN KERATINOCYTES: MOLECULAR MECHANISMS OF ACTION.

The effect of plant flavonoids on intercellular adhesion molecule-1 (ICAM-1) expression in human keratinocyte was investigated. ICAM-1 is known to mediate skin inflammation. Among the flavonoids tested, taxifolin was the most potent in inhibiting interferon γ (IFN γ)-induced ICAM-1 protein... Read More

December 11, 2015

A SMALL-MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL.

This study by researchers at the H. Lee Moffitt Cancer Center and Research Institute demonstrated how MatTek’s Melanoma in vitro human skin tissue equivalent can be used to investigate both the efficacy of potential melanoma therapeutic agents and their potential... Read More

December 11, 2015

UPREGULATION OF SOX9 INHIBITS THE GROWTH OF HUMAN AND MOUSE MELANOMAS AND RESTORES THEIR SENSITIVITY TO RETINOIC ACID.

This study by researchers at the National Cancer Institute (NIH) demonstrated that MatTek’s Melanoma in vitro human skin tissue equivalent can be used to investigate both the efficacy and cytotoxicity of potential malignant melanoma treatments. Treatments for primary and metastatic... Read More

December 11, 2015

EFFECT OF LAUNDERING ON ABILITY OF GLOVE FABRICS TO DECREASE THE PENETRATION OF ORGANOPHOSPHATE INSECTICIDES THROUGH IN VITRO EPIDERMAL SYSTEMS.

Researchers at Virginia Tech University examined two knit glove fabrics, one of 100% cotton and one of 100% polypropylene, for their capability to decrease the penetration of the organo-phosphate insecticides (OPs), azinphos-methyl and paraoxon after 4 h at field concentrations... Read More

December 11, 2015

HUMAN MELANOMA DEVELOPMENT IN RECONSTRUCTED SKIN MODELS.

Human skin reconstructs are three dimensional in vitro models consisting of a co-culture of epidermal keratinocytes and melanocytes plated onto a dermal substrate. In contrast to cells in monolayer culture, tissue-engineered skin equivalents contain well-developed epidermal layers with normal melanocytes... Read More

Reference Libraries

FLAVONOIDS DIFFERENTIALLY REGULATE IFN-GAMMA-INDUCED ICAM-1 EXPRESSION IN HUMAN KERATINOCYTES: MOLECULAR MECHANISMS OF ACTION.

A SMALL-MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL.

UPREGULATION OF SOX9 INHIBITS THE GROWTH OF HUMAN AND MOUSE MELANOMAS AND RESTORES THEIR SENSITIVITY TO RETINOIC ACID.

EFFECT OF LAUNDERING ON ABILITY OF GLOVE FABRICS TO DECREASE THE PENETRATION OF ORGANOPHOSPHATE INSECTICIDES THROUGH IN VITRO EPIDERMAL SYSTEMS.

HUMAN MELANOMA DEVELOPMENT IN RECONSTRUCTED SKIN MODELS.

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