Reference Libraries

August 26, 2024

16-Kauren-2-beta-18,19-triol inhibits melanosome transport in melanocytes by down-regulation of melanophilin expression

Rab27a, Mlph, and MyoVa form a tripartite complex and relate to melanosome distribution. Melanophilin (Mlph) acts as a linker protein between Rab27a and MyoVa. The biological activity and function of 16-kauren on the expression of Mlph has not yet been... Read More

August 23, 2024

Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract

The exposure to inhaled carbon nanotubes (CNT) may have adverse effects on workers upon chronic exposure. In order to assess the toxicity of inhaled nanoparticles in a physiologically relevant manner, an air–liquid interface culture of mono and cocultures of respiratory... Read More

August 23, 2024

Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals

Ebola virus (EBOV) is the causative agent of the often-fatal Ebola virus disease (EVD) characterized by hemorrhagic fever in humans and non-human primates. Sexual transmission from male survivors has been at the origin of multiple outbreak flare-ups between 2015 and... Read More

August 23, 2024

In vitro prediction of the performance or equivalence, of different formulations of the same drug substance using a 3D reconstructed human intestinal tissue model: application to generics or drugs in development

“The BCS (Biopharmaceutics Classification System)-based biowaiver approach is intended to reduce the need for in vivo bioequivalence studies in Human, in order to lower costs of development, increase the market access for generic drugs and from an ethical point of... Read More

August 23, 2024

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women

Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs) for clinical use. We used the Nicotiana platform to produce... Read More

Reference Libraries

16-Kauren-2-beta-18,19-triol inhibits melanosome transport in melanocytes by down-regulation of melanophilin expression

Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract

Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals

In vitro prediction of the performance or equivalence, of different formulations of the same drug substance using a 3D reconstructed human intestinal tissue model: application to generics or drugs in development

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women

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