Reference Libraries

December 11, 2015

ACTIVATION OF NOTCH SIGNALING IN KERATINOCYTES (KC’S) IS NECESSARY AND SUFFICIENT TO CREATE MATURE HUMAN EPIDERMIS.

The signaling system regulating the highly coordinated and programmed series of molecular events that generate a mature, fully differentiated and cornified epidermis is unknown. To determine if Notch ligands and receptors that regulate cell fate decisions in other organ systems... Read More

December 11, 2015

EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.

Toxic epidermal necrolysis (TEN or Lyell’s syndrome) is a severe adverse drug reaction that results in extensive necrolysis of the skin due to large scale Fas-FasL mediated keratinocyte apoptosis. The signaling pathways leading to the rapid upregulation of keratinocyte FasL... Read More

December 11, 2015

LONG TERM CULTURE OF PSEUDOSTRATIFIED TRACHEAL BRONCHIAL EPIAIRWAY™ TISSUES.

This study by scientists at MatTek Corp. demonstrated that MatTek’s EpiAirway in vitro human tracheal/bronchial tissue equivalent remains viable for up to 27 DAYS and can therefore be used in long term studies of chronic respiratory diseases. The highly differentiated... Read More

December 11, 2015

GENE EXPRESSION PROFILING OF SKIN CARCINOGENSIS IN MICE.

This study by researchers at the University of Leicester and Unilever’s Safety Environmental Assurance Centre (SEAC) demonstrated that MatTek’s EpiDerm human skin tissue equivalents can be kept in a viable state for up to 23 DAYS. The overall goal of... Read More

December 11, 2015

MODELLING THE HUMAN BRONCHI AND ITS RESPONSES IN VITRO.

This study by researchers at Unilever’s Safety and Environment Assurance Centre (SEAC) demonstrated that MatTek’s EpiAirway in vitro human tracheal/bronchial tissue equivalent displayed significant morphological and biochemical correlation with both in vitro and in vivo models, re-confirming the potential value... Read More

Reference Libraries

ACTIVATION OF NOTCH SIGNALING IN KERATINOCYTES (KC’S) IS NECESSARY AND SUFFICIENT TO CREATE MATURE HUMAN EPIDERMIS.

EVIDENCE THAT NITRIC OXIDE IS AN UPSTREAM MEDIATOR OF FASL-MEDIATED KERATINOCYTE APOPTOSIS IN TOXIC EPIDERMAL NECROLYSIS.

LONG TERM CULTURE OF PSEUDOSTRATIFIED TRACHEAL BRONCHIAL EPIAIRWAY™ TISSUES.

GENE EXPRESSION PROFILING OF SKIN CARCINOGENSIS IN MICE.

MODELLING THE HUMAN BRONCHI AND ITS RESPONSES IN VITRO.

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