Reference Libraries

December 11, 2015

A COMPARISON STUDY OF FOUR IN VITRO PHOTOTOXICITY SYSTEMS.

Four in vitro phototoxicity systems were evaluated to determine how closely each method would reproduce the others. Eleven materials were used to evaluate these methods. All eleven materials were run in each system. Phototoxicity was evaluated using the MatTek EPI-100... Read More

December 11, 2015

DEVELOPMENT AND CHARACTERIZATION OF 3D PSORIATIC TISSUE MODEL.

Psoriasis is an inflammatory skin disease marked by hyperproliferation and abnormal keratinocyte differentiation that affects about 2% of the global population. In this study, we developed a human cell based in vitro psoriatic tissue model from psoriatic fibroblasts and normal... Read More

December 11, 2015

USE OF THE MATTEK EPI-100 IN VITRO SYSTEM TO SCREEN ANTIOXIDANT EFFICACY.

In this study, scientists at R. Thomas Stephens & Associates present an in vitro method to evaluate the efficacy of antioxidants and antioxidant formulations. The premise of this research is that exposure of human skin equivalents, specifically the commercially available... Read More

December 11, 2015

DELPHINIDIN INDUCES EPIDERMAL DIFFERENTIATION AND INHIBITS PROLIFERATION AND INFLAMMATION IN A THREE-DIMENSIONAL RECONSTITUTED SKIN MODEL OF PSORIASIS.

Psoriasis is a chronic, inflammatory skin disease characterized by epidermal hyperproliferation and aberrant keratinocyte differentiation. Several lines of evidence suggest that intrinsic alterations of the epidermis may play an important role in the pathogenesis of psoriasis. Identification of natural agents... Read More

December 11, 2015

HYPERPIGMENTATION IN HUMAN SOLAR LENTIGO IS PROMOTED BY HEPARANASE-INDUCED LOSS OF HEPARAN SULFATE CHAINS AT THE DERMAL–EPIDERMAL JUNCTION.

Background: Skin pigmentation induced by ultraviolet B radiation is caused in part by inflammation mediated by cytokines secreted from keratinocytes and fibroblasts in the irradiated area. Heparanase is also activated in the irradiated skin, and this leads to loss of... Read More

Reference Libraries

A COMPARISON STUDY OF FOUR IN VITRO PHOTOTOXICITY SYSTEMS.

DEVELOPMENT AND CHARACTERIZATION OF 3D PSORIATIC TISSUE MODEL.

USE OF THE MATTEK EPI-100 IN VITRO SYSTEM TO SCREEN ANTIOXIDANT EFFICACY.

DELPHINIDIN INDUCES EPIDERMAL DIFFERENTIATION AND INHIBITS PROLIFERATION AND INFLAMMATION IN A THREE-DIMENSIONAL RECONSTITUTED SKIN MODEL OF PSORIASIS.

HYPERPIGMENTATION IN HUMAN SOLAR LENTIGO IS PROMOTED BY HEPARANASE-INDUCED LOSS OF HEPARAN SULFATE CHAINS AT THE DERMAL–EPIDERMAL JUNCTION.

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