Reference Libraries

December 11, 2015

IDENTIFYING CELL AND MOLECULAR STRESS AFTER RADIATION IN A THREE-DIMENSIONAL (3-D) MODEL OF ORAL MUCOSITIS.

Mucositis is a debilitating adverse effect of chemotherapy and radiation treatment. It is important to develop a simple and reliable in vitro model, which can routinely be used to screen new drugs for prevention and treatment of mucositis. Furthermore, identifying... Read More

December 11, 2015

THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.

Close association exists between melanocytes, the pigment melanin-producing cells in the body, and their neighboring keratinocytes. Keratinocytes are the pigment recipients and skin pigmentation is the result of this interaction. While the chemical basis of melanin production (melanogenesis) is well... Read More

December 11, 2015

EFFECTS OF ANTIOXIDANT INGREDIENTS ON HUMAN SKIN: FROM CELL CULTURE TESTING TO HUMAN CLINICAL TRIALS.

Cosmetic chemists have included Vitamins A, C, and 12 and other similar ingredients into skin care and cosmetic products for many years now. These ingredients and their derivatives were originally incorporated into those products for their effects in improving the... Read More

December 11, 2015

NEW RESULTS WITH MELANODERM™, AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES.

We have previously reported on the successful incorporation of normal human melanocytes (NHM) into a highly differentiated, three-dimensional tissue culture model of human epidermis (JID, 104(4), 616, 1995). Melanocytes exhibited dendritic morphology, were localized in the basal cell layer, and... Read More

December 11, 2015

IN VITRO TESTING FOR PHOTOTOXIC POTENTIAL USING THE EPIDERM 3-D RECONSTRUCTED SKIN MODEL.

An in vitro photocytotoxicity model using mouse 3T3 fibroblasts (the 3T3 NRU PT) has recently been validated for the detection of the phototoxic potential of test substances. Although the 3T3 NRU PT has been demonstrated to detect the phototoxic potential... Read More

Reference Libraries

IDENTIFYING CELL AND MOLECULAR STRESS AFTER RADIATION IN A THREE-DIMENSIONAL (3-D) MODEL OF ORAL MUCOSITIS.

THE PROTEASE-ACTIVATED RECEPTOR 2 REGULATES PIGMENTATION VIA KERATINOCYTE-MELANOCYTE INTERACTIONS.

EFFECTS OF ANTIOXIDANT INGREDIENTS ON HUMAN SKIN: FROM CELL CULTURE TESTING TO HUMAN CLINICAL TRIALS.

NEW RESULTS WITH MELANODERM™, AN EPIDERMAL MODEL CONTAINING FUNCTIONAL MELANOCYTES.

IN VITRO TESTING FOR PHOTOTOXIC POTENTIAL USING THE EPIDERM 3-D RECONSTRUCTED SKIN MODEL.

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