Reference Libraries

December 11, 2015

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

The bovine corneal opacity and permeability (BCOP) test has been adopted by OECD for the identification of corrosive and severe ocular irritants (GHS category 1) for single component substances and multicomponent formulations. Eye irritation tests with human (EIT) reconstructed tissue... Read More

December 11, 2015

N,N-DICHLORO-2, 2-DIMETHYLTAURINE, N-MONOCHLORO-2, 2-DIMETHYLTAURINE, AND N-CHLOROTAURINE ARE SAFE AND EFFECTIVE BACTERICIDAL AGENTS IN CORNEAL MODELS.

Background: N-chlorotaurine, NVC-422 (N,N-dichloro-dimethyltaurine) and NVC-612 (N-monochloro-dimethyltaurine) are potent anti-infective agents useful for the treatment of conjunctivitis and keratitis. The aim of this study is to show that these compounds are safe in an EpiOcular model and effective in corneas... Read More

December 11, 2015

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

There is an increasing need by the tobacco industry to evaluate the irritation and inflammation potential of tobacco products to support product development goals, for sound product stewardship, and likely regulatory safety tests. The use of in vitro human cell... Read More

December 11, 2015

NOVEL IN VITRO METHODOLOGY EVALUATING POTENTIAL MUCOSAL IRRITATION OF ORAL CARE FORMULATIONS.

This study by researchers at The Procter & Gamble Co. demonstrated that MatTek’s EpiOral in vitro human buccal (inner cheek) tissue equivalent provided a quick, reproducible method for evaluating the irritation potential of oral care excipients and prototype formulations, the... Read More

December 11, 2015

EVALUATION OF TISSUE ENGINEERED MODELS OF THE ORAL MUCOSA TO INVESTIGATE ORAL CANDIDIASIS.

Candida albicans is a commensal organism that can be isolated from the majority of healthy individuals. However, in certain susceptible individuals C. albicans can become pathogenic leading to the mucocutaneous infection; oral candidiasis. Murine models and in vitro monolayer cultures... Read More

Reference Libraries

PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).

N,N-DICHLORO-2, 2-DIMETHYLTAURINE, N-MONOCHLORO-2, 2-DIMETHYLTAURINE, AND N-CHLOROTAURINE ARE SAFE AND EFFECTIVE BACTERICIDAL AGENTS IN CORNEAL MODELS.

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

NOVEL IN VITRO METHODOLOGY EVALUATING POTENTIAL MUCOSAL IRRITATION OF ORAL CARE FORMULATIONS.

EVALUATION OF TISSUE ENGINEERED MODELS OF THE ORAL MUCOSA TO INVESTIGATE ORAL CANDIDIASIS.

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