Reference Libraries

December 11, 2015

Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy

Gene therapy could offer improvement in the treatment of glaucoma compared to the current standard of lowering intraocular pressure. We have developed and characterized non-viral gemini surfactant-phospholipid nanoparticles (GL-NPs) for intravitreal and topical administration. Optimized GL-NPs (size range 150-180 nm)... Read More
December 11, 2015

STUDIES ON VAGINAL INNATE IMMUNITY IN THE EPIVAGINAL MODEL.

This study by researchers at Boston University School of Medicine and MatTek Corp. demonstrated that the EpiVaginal full thickness human cervico-vaginal tissue equivalent can provide valuable information on molecular mechanisms of vaginal innate immunity, and serve as a test system... Read More
December 11, 2015

IDENTIFICATION OF TIGHT JUNCTION MODULATING LIPIDS.

Tight junctions (TJs) play an important role in regulating paracellular drug transport. The aim of this study was to identify lipids that rapidly and reversibly alter transepithelial electrical resistance (TER) and/or TJ permeability in epithelial tissue. In this study, we... Read More