Reference Libraries

December 11, 2015

NOVEL IN VITRO METHODOLOGY EVALUATING POTENTIAL MUCOSAL IRRITATION OF ORAL CARE FORMULATIONS.

This study by researchers at The Procter & Gamble Co. demonstrated that MatTek’s EpiOral in vitro human buccal (inner cheek) tissue equivalent provided a quick, reproducible method for evaluating the irritation potential of oral care excipients and prototype formulations, the... Read More

December 11, 2015

ASSESSMENT OF DERMAL TOXICITY OF NANOSILICA USING CULTURED KERATINOCYTES, A HUMAN SKIN EQUIVALENT MODEL AND AN IN VIVO MODEL.

This study by researchers at Korea University College of Medicine and the National Institute of Toxicological Research (Korea) demonstrated how MatTek’s EpiDerm in vitro 3-D human skin tissue equivalent can be used to test the skin irritation potential of nanosilica... Read More

December 11, 2015

THE USE OF FLUORESCENTLY LABELED NANOPARTICLES TO DETERMINE THE EFFECT OF PARTICLE SIZE ON TRANSLOCATION FROM THE LUNG.

Nanoparticles or ultrafine particles, are particles generally considered to be less than 100nm in size. These particles have been implicated in morbidity and other adverse reactions. Due to their small size, these particles may translocate from the lung to remote... Read More

December 11, 2015

EVALUATION OF TISSUE ENGINEERED MODELS OF THE ORAL MUCOSA TO INVESTIGATE ORAL CANDIDIASIS.

Candida albicans is a commensal organism that can be isolated from the majority of healthy individuals. However, in certain susceptible individuals C. albicans can become pathogenic leading to the mucocutaneous infection; oral candidiasis. Murine models and in vitro monolayer cultures... Read More

December 11, 2015

EPIGINGIVAL™ (GIN-100) TISSUE MODELS FOR ORAL IRRITATION STUDIES.

This study by scientists at the University of Washington, University of Iowa and MatTek Corp. demonstrated that MatTek’s EpiOral and EpiGingival in vitro human oral tissue equivalents can be used to provide a quick, reproducible method for evaluating the irritation... Read More

Reference Libraries

NOVEL IN VITRO METHODOLOGY EVALUATING POTENTIAL MUCOSAL IRRITATION OF ORAL CARE FORMULATIONS.

ASSESSMENT OF DERMAL TOXICITY OF NANOSILICA USING CULTURED KERATINOCYTES, A HUMAN SKIN EQUIVALENT MODEL AND AN IN VIVO MODEL.

THE USE OF FLUORESCENTLY LABELED NANOPARTICLES TO DETERMINE THE EFFECT OF PARTICLE SIZE ON TRANSLOCATION FROM THE LUNG.

EVALUATION OF TISSUE ENGINEERED MODELS OF THE ORAL MUCOSA TO INVESTIGATE ORAL CANDIDIASIS.

EPIGINGIVAL™ (GIN-100) TISSUE MODELS FOR ORAL IRRITATION STUDIES.

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