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December 11, 2015

RECONSTRUCTION OF VAGINAL TISSUE MODEL FOR HIV INFECTION.

The HIV/AIDS epidemic is continuing to escalate worldwide and it is estimated that through the year 2000, more than 34 million people have already been infected with the virus. Daily, 16,000 individuals acquire HIV-1 infection and the majority of all... Read More

December 11, 2015

IN VITRO ASSESSMENT OF PERSONAL CARE PRODUCTS FOR VAGINAL IRRITATION USING 3D TISSUE CONSTRUCTS.

Three dimensional (3D) human vaginal-ectocervical tissue constructs may be a relevant in vitro model to rapidly screen for vaginal mucosal irritation potential of raw materials and final formulations. Here we report results from a study with an in vitro vaginal... Read More

December 11, 2015

STUDIES ON VAGINAL INNATE IMMUNITY IN THE EPIVAGINAL MODEL SYSTEM.

As stated in the “Conclusions” section, this study by MatTek Corp. scientists demonstrated that the EpiVaginal human ectocervical-vaginal tissue equivalent provided valuable information on molecular mechanisms of vaginal innate immunity, and served as a test system to determine the effects... Read More

December 11, 2015

ORGANOTYPIC HUMAN VAGINAL-ECTOCERVICAL TISSUE MODEL FOR IRRITATION STUDIES OF SPERMICIDES, MICROBICIDES, AND FEMININE-CARE PRODUCTS.

This study by scientists at Boston University School of Medicine and MatTek Corp. demonstrated that MatTek’s EpiVaginal in vitro human cervico-vaginal tissue equivalent is a highly reproducible, non-animal means to assess the irritation potential of topically applied contraceptives, microbicides and... Read More

December 11, 2015

THE RETROCYCLIN ANALOGUE RC-101 PREVENTS HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INFECTION OF A MODEL HUMAN CERVICOVAGINAL TISSUE CONSTRUCT.

This study by researchers at the University of Central Florida, University of Pittsburgh and UCLA School of Medicine demonstrated that MatTek’s EpiVaginal human vaginal-ectocervical tissue equivalent can be used to test the toxicity and efficacy of potential HIV-1 topical microbicides.... Read More

Reference Libraries

RECONSTRUCTION OF VAGINAL TISSUE MODEL FOR HIV INFECTION.

IN VITRO ASSESSMENT OF PERSONAL CARE PRODUCTS FOR VAGINAL IRRITATION USING 3D TISSUE CONSTRUCTS.

STUDIES ON VAGINAL INNATE IMMUNITY IN THE EPIVAGINAL MODEL SYSTEM.

ORGANOTYPIC HUMAN VAGINAL-ECTOCERVICAL TISSUE MODEL FOR IRRITATION STUDIES OF SPERMICIDES, MICROBICIDES, AND FEMININE-CARE PRODUCTS.

THE RETROCYCLIN ANALOGUE RC-101 PREVENTS HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INFECTION OF A MODEL HUMAN CERVICOVAGINAL TISSUE CONSTRUCT.

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