Reference Libraries

December 11, 2015

ORGANOTYPIC HUMAN ORAL TISSUE MODELS FOR EVALUATION OF ORAL CARE PRODUCTS.

Oral irritation can result from exposure of the soft tissue to dentifrice and oral rinse formulations. In vitro tissue models (MatTek Corporation) produced from normal human oral keratinocytes were exposed to common oral care excipients, dentifrice supernatants and mouth rinses... Read More

December 11, 2015

HUMAN TISSUE MODEL FOR VAGINAL IRRITATION STUDIES.

Recently, EpiVaginal™, a tissue culture-based model of the vaginal epithelium, has been developed. Normal, human ectocervico-vaginal (ECV) epithelial cells were induced to form a three-dimensional tissue using specially formulated serum free medium. The in vitro tissue reproduces many of the... Read More

December 11, 2015

TGF-á REGULATES TLR EXPRESSION AND FUNCTION ON EPIDERMAL KERATINOCYTES.

This study by researchers at the UCLA School of Medicine and the University of Iowa Hospitals and Clinics demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used to investigate how TGF-á, a growth and differentiation factor present during... Read More

December 11, 2015

NEW EPIDERMAL MODEL FOR DERMAL IRRITANCY TESTING.

A model of the human epidermis, EpiDerm™, based on neonatal, foreskin-derived normal human epidermal keratinocytes (NHEK) has been developed over the past 18 months at MatTek Corporation. Cultured in easily handled Millicell® CM (Millipore Corp.) cell culture inserts, the model... Read More

December 11, 2015

Reference Libraries

ORGANOTYPIC HUMAN ORAL TISSUE MODELS FOR EVALUATION OF ORAL CARE PRODUCTS.

HUMAN TISSUE MODEL FOR VAGINAL IRRITATION STUDIES.

TGF-á REGULATES TLR EXPRESSION AND FUNCTION ON EPIDERMAL KERATINOCYTES.

NEW EPIDERMAL MODEL FOR DERMAL IRRITANCY TESTING.

HUMAN VAGINAL—ECTOCERVIAL TISSUE MODEL TO TEST THE IRRITATION POTENTIAL OF CONTRACEPTIVE AND VAGINAL-CARE PRODUCTS.

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