Reference Libraries

December 11, 2015

IDENTIFICATION OF INTELLIGENT BIOMARKERS OF EXPOSURE AND HARM IN THE RESPIRATORY EPITHELIAL TO TOBACCO SMOKE COMPONENTS.

This study by researchers in the Cardiff University School of Biosciences (Wales/UK) demonstrated how MatTek’s EpiAirway in vitro human tracheal/ bronchial tissue equivalent can be used to study the early gene response of human respiratory epithelia to tobacco smoke component... Read More

December 11, 2015

ASSESSMENT OF ORGANOTYPIC EPIVAGINALTM TISSUE MODEL TO SCREEN IRRITATION POTENTIAL OF CHEMICALS.

A predictive test system for assessing the vaginal irritation of chemicals and formulations will have far reaching application in industries involved in feminine care products. The vaginal mucosa is commonly exposed to chemicals or therapeutic agents that can cause irritation/inflammation... Read More

December 11, 2015

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

Dendritic cells (DC) play a key role in the initiation of immune response by recognizing, internalizing, processing, and presenting antigens to T cells. However, DC function can be altered by environmental factors, pharmaceutical agents, and exogenous chemicals. These perturbations to... Read More

December 11, 2015

INJURY ENHANCES TLR2 FUNCTION AND ANTIMICROBIAL PEPTIDE EXPRESSION THROUGH A VITAMIN D–DEPENDENT MECHANISM.

This study by researchers at UCSD, UCLA, UCSF, the University of Michigan and Schering AG demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used to study the effects of vitamin D3 on the human epidermis, specifically on keratinocytes,... Read More

December 11, 2015

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by... Read More

Reference Libraries

IDENTIFICATION OF INTELLIGENT BIOMARKERS OF EXPOSURE AND HARM IN THE RESPIRATORY EPITHELIAL TO TOBACCO SMOKE COMPONENTS.

ASSESSMENT OF ORGANOTYPIC EPIVAGINALTM TISSUE MODEL TO SCREEN IRRITATION POTENTIAL OF CHEMICALS.

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

INJURY ENHANCES TLR2 FUNCTION AND ANTIMICROBIAL PEPTIDE EXPRESSION THROUGH A VITAMIN D–DEPENDENT MECHANISM.

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

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