Reference Libraries

December 11, 2015

DISRUPTION OF TIGHT JUNCTIONS BY CELLULOSE SULFATE FACILITATES HIV INFECTION: MODEL OF MICROBICIDE SAFETY.

This study by researchers in the Departments of Pediatrics, Microbiology-Immunology and Medicine at Albert Einstein College of Medicine demonstrated that MatTek’s EpiVaginal in vitro 3-D human cervico-vaginal tissue equivalent can be used to model potential epithelial barrier disruption caused by... Read More

December 11, 2015

VISUALIZING INDIVIDUAL, FLUORESCENTLY TAGGED HIV-1 VIRIONS IN CERVICAL TISSUE.

This study by researchers at the Northwestern University School of Medicine demonstrated how MatTek’s EpiVaginal human cervico-vaginal tissue equivalent can be used in the development of methodologies to visualize the interaction of HIV-1 virus with cervical mucosa/tissue. Background: The majority... Read More

December 11, 2015

A RECOMBINANT SIALIDASE FUSION PROTEIN EFFECTIVELY INHIBITS HUMAN PARAINFLUENZA VIRAL INFECTION IN VITRO AND IN VIVO.

Background: The first step in infection by human parainfluenza viruses (HPIVs) is binding to the surface of respiratory epithelial cells via interaction between viral receptor-binding molecules and sialic acid–containing receptors. DAS181, a recombinant sialidase protein containing the catalytic domain of... Read More

December 11, 2015

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by... Read More

December 11, 2015

Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model: Morphologic and Immunologic Effects

Estrogen and progesterone regulate proliferation and differentiation of epithelial cells in the female genital tract. We investigated the effects of these hormones on reconstructed human organotypic vaginal epithelial tissue models (EpiVaginal). We ascertained that epithelial cells in the tissue models... Read More

Reference Libraries

DISRUPTION OF TIGHT JUNCTIONS BY CELLULOSE SULFATE FACILITATES HIV INFECTION: MODEL OF MICROBICIDE SAFETY.

VISUALIZING INDIVIDUAL, FLUORESCENTLY TAGGED HIV-1 VIRIONS IN CERVICAL TISSUE.

A RECOMBINANT SIALIDASE FUSION PROTEIN EFFECTIVELY INHIBITS HUMAN PARAINFLUENZA VIRAL INFECTION IN VITRO AND IN VIVO.

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model: Morphologic and Immunologic Effects

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