December 11, 2015
INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.
In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by... Read More
