Reference Libraries

December 11, 2015

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

EpiDerm (MatTek Co., MA) is a reconstituted human skin equivalent which exhibits morphological and growth characteristics similar to human skin. This model has previously been utilized to evaluate the cytotoxicity and irritant potential of various cosmetic and household products. In... Read More

December 11, 2015

STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.

According to the target theory of radiation-induced effects (1), a central tenet of radiation biology, DNA damage occurs during or very shortly after irradiation of the nuclei in targeted cells, and the potential for biological consequences can be expressed within... Read More

December 11, 2015

A HUMAN ORAL TISSUE MODEL TO EVALUATE TOXICITY AND ANTI-HIV ACTIVITY OF THE SPERMICIDE-MICROBICIDE, NONOXYNOL-9M.

This study by researchers at the University of Washington, the Fred Hutchinson Cancer Research Center and MatTek Corp. demonstrated that a new form of MatTek’s EpiOral full thickness human buccal tissue equivalent containing Langerhans Cells appears to be useful in... Read More

December 11, 2015

THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.

This study by researchers at Genentech demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used to study the immunopathology of psoriasis. IL-19, IL-20, IL-22, IL-24, and IL-26 are members of the IL-10 family of cytokines that have been... Read More

December 11, 2015

EXPRESSION AND FUNCTION OF BACTERICIDAL/PERMEABILITY – INCREASING PROTEIN IN HUMAN GENITAL TRACT EPITHELIAL CELLS.

This study by researchers at Brigham and Women’s Hospital/Harvard Medical School demonstrated that MatTek’s EpiVaginal human cervico-vaginal tissue equivalent expresses bactericidal/permeability-increasing protein (BPI) and that this protein’s role in regulating bacterial colonization in the genital mucosa can be studied in... Read More

Reference Libraries

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.

A HUMAN ORAL TISSUE MODEL TO EVALUATE TOXICITY AND ANTI-HIV ACTIVITY OF THE SPERMICIDE-MICROBICIDE, NONOXYNOL-9M.

THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.

EXPRESSION AND FUNCTION OF BACTERICIDAL/PERMEABILITY – INCREASING PROTEIN IN HUMAN GENITAL TRACT EPITHELIAL CELLS.

Get the latest