Reference Libraries

December 11, 2015

THE USE OF PLASMACYTOID DENDRITIC CELLS FOR ALLERGENICITY SCREENING OF CHEMICALS.

This study by MatTek Corp. scientists demonstrated that increased expression of CD86 in pDC’s, a subset of MatTek’s Human Dendritic Cells, can be used as a sensitive and specific marker for the identification of chemical allergens. Also see TR-449 –... Read More

December 11, 2015

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

Dendritic cells (DC) play a key role in the initiation of immune response by recognizing, internalizing, processing, and presenting antigens to T cells. However, DC function can be altered by environmental factors, pharmaceutical agents, and exogenous chemicals. These perturbations to... Read More

December 11, 2015

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by... Read More

December 11, 2015

TRICHOMONAS VAGINALIS LIPOPHOSPHOGLYCAN TRIGGERS A SELECTIVE UPREGULATION OF CYTOKINES BY HUMAN FEMALE REPRODUCTIVE TRACT EPITHELIAL CELLS.

This study by researchers at Brigham and Women’s Hospital/Harvard Medical School, Cornell University, Boston University School of Medicine, and SUNY Upstate Medical University demonstrated that MatTek’s EpiVaginal human cervico-vaginal tissue equivalent can be used to study in vitro the molecular... Read More

December 11, 2015

Reference Libraries

THE USE OF PLASMACYTOID DENDRITIC CELLS FOR ALLERGENICITY SCREENING OF CHEMICALS.

IN VITRO MODEL FOR IMMUNOTOXICITY: SURFACE MARKER EXPRESSION AND CYTOKINE RELEASE IN NORMAL HUMAN DENDRITIC CELLS (DC-100).

INHIBITION OF NIPAH VIRUS INFECTION IN VIVO: TARGETING AN EARLY STAGE OF PARAMYXOVIRUS FUSION ACTIVATION DURING VIRAL ENTRY.

TRICHOMONAS VAGINALIS LIPOPHOSPHOGLYCAN TRIGGERS A SELECTIVE UPREGULATION OF CYTOKINES BY HUMAN FEMALE REPRODUCTIVE TRACT EPITHELIAL CELLS.

IRRITATION TESTING OF CONTRACEPTIVE AND FEMININE-CARE PRODUCTS USING EPIVAGINAL, AN IN VITRO HUMAN VAGINAL-ECTOCERVICAL TISSUE MODEL.

Get the latest