Reference Libraries

December 11, 2015

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

EpiDerm (MatTek Co., MA) is a reconstituted human skin equivalent which exhibits morphological and growth characteristics similar to human skin. This model has previously been utilized to evaluate the cytotoxicity and irritant potential of various cosmetic and household products. In... Read More

December 11, 2015

A HUMAN ORAL TISSUE MODEL TO EVALUATE TOXICITY AND ANTI-HIV ACTIVITY OF THE SPERMICIDE-MICROBICIDE, NONOXYNOL-9M.

This study by researchers at the University of Washington, the Fred Hutchinson Cancer Research Center and MatTek Corp. demonstrated that a new form of MatTek’s EpiOral full thickness human buccal tissue equivalent containing Langerhans Cells appears to be useful in... Read More

December 11, 2015

ACTIVATED CD34-DERIVED LANGERHANS CELLS MEDIATE TRANSINFECTION WITH HUMAN IMMUNODEFICIENCY VIRUS.

This study by researchers at Northwestern University’s Feinberg School of Medicine and the University of Illinois at Chicago College of Medicine demonstrated that it was possible to create and isolate a Langerhans Cells (LCs) subset of MatTek Human Dendritic Cells... Read More

December 11, 2015

THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.

The objective of this study was the pharmaco-toxicological understanding of the constituents of an authenticated herbal mixture. The mixture was prepared by maceration in ethanol and subsequent dilution to produce a topically applied lotion, for which the intended target conditions... Read More

December 11, 2015

NOREPINEPHRINE INHIBITS LANGERHANS CELL ACTIVATION BY ALTERING CYTOKINE RELEASE.

This study by researchers at Estee Lauder Research Laboratories and Cornell’s Weill Medical College demonstrated that norepinephrine binding to beta adrenergic receptors expressed on the surface of human Langerhans Cells (MatTek’s Human Dendritic Cells) mediated the decrease in immune function... Read More

Reference Libraries

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

A HUMAN ORAL TISSUE MODEL TO EVALUATE TOXICITY AND ANTI-HIV ACTIVITY OF THE SPERMICIDE-MICROBICIDE, NONOXYNOL-9M.

ACTIVATED CD34-DERIVED LANGERHANS CELLS MEDIATE TRANSINFECTION WITH HUMAN IMMUNODEFICIENCY VIRUS.

THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.

NOREPINEPHRINE INHIBITS LANGERHANS CELL ACTIVATION BY ALTERING CYTOKINE RELEASE.

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