Reference Libraries

June 13, 2023

Development of a micronucleus test using the EpiAirway™ organotypic human airway model

The use of organotypic human tissue models in genotoxicity has increased as an alternative to animal testing. Genotoxicity is generally examined using a battery of in vitro assays such as Ames and micronucleus (MN) tests that cover gene mutations and... Read More

June 13, 2023

Single-cell analysis of Kaposi’s sarcoma-associated herpesvirus infection in three-dimensional air-liquid interface culture model

The oral cavity is the major site for transmission of Kaposi’s sarcoma-associated herpesvirus (KSHV), but how KSHV establishes infection and replication in the oral epithelia remains unclear. Here, we report a KSHV spontaneous lytic replication model using fully differentiated, three... Read More

April 7, 2023

Bioengineering of Novel Organotypic 3D Human Liver/Hepatocyte Tissue Model for Drug Induced Liver Injury/Toxicity Studies

Development of a human primary cell-based 3D organotypic liver/hepatocyte tissue model with polarized hepatic morphology that maintains high level expression of major liver associated drug metabolizing enzymes is an attractive alternative platform to study acute and chronic liver toxicity and drug induced... Read More

April 7, 2023

Development of an in vitro 3D Human Kidney Proximal Tubular Epithelial Tissue Model

The renal proximal tubular (PT) region is the most common site for a compound-specific kidney injury. The PT region is responsible for essential kidney functions, including reabsorption of low molecular weight proteins, solutes, and glucose, secretion of acids, and clearance of administered medications.... Read More

April 7, 2023

Arctigenin-Enriched Burdock Seed Oil (ABSO): A New Skin Brightening Botanical Extract

The Arctium lappa L. plant, commonly known as burdock, has been used therapeutically for hundreds of years. Arctigenin (ATG) is an active ingredient in burdock, albeit at low quantities or mostly in the form of acrtiin (arctigenin-4-glucoside). ATG has been... Read More

Reference Libraries

Development of a micronucleus test using the EpiAirway™ organotypic human airway model

Single-cell analysis of Kaposi’s sarcoma-associated herpesvirus infection in three-dimensional air-liquid interface culture model

Bioengineering of Novel Organotypic 3D Human Liver/Hepatocyte Tissue Model for Drug Induced Liver Injury/Toxicity Studies

Development of an in vitro 3D Human Kidney Proximal Tubular Epithelial Tissue Model

Arctigenin-Enriched Burdock Seed Oil (ABSO): A New Skin Brightening Botanical Extract

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