Reference Libraries

December 11, 2015

IMPROVED METHOD FOR THE GENERATION OF LONG LIVED AND FUNCTIONALLY ACTIVE DENDRITIC/LANGERHANS CELLS FROM CD34+ PROGENITOR CELLS.

The difficulty in harvesting large number of cells, short survival time, and rapid phenotypic changes in culture have prevented the widespread use of human dendritic cells (DC)/Langerhans cells (LC) for fundamental studies involving these key immunological cells. Here MatTek scientists... Read More

December 11, 2015

LANGERHANS CELLS RELEASE PROSTAGLANDIN D2 IN RESPONSE TO NICOTINIC ACID.

This study by researchers at Arena Pharmaceuticals demonstrated that MatTek’s Human Dendritic Cells can be used to identify the mechanism of a drug’s in vivo adverse side effects. Nicotinic acid, used for atherosclerosis treatment, has an adverse effect of skin... Read More

December 11, 2015

IN VITRO DERIVED DENDRITIC CELLS TRANS-INFECT CD4 T CELLS PRIMARILY WITH SURFACE-BOUND HIV-1 VIRIONS.

This study by researchers at the University of California at San Francisco (UCSF) demonstrated that MatTek’s Human Dendritic Cells can be used to study the infection mechanism of HIV-1 virus from dendritic cells to T cells. In the prevailing model... Read More

December 11, 2015

STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.

According to the target theory of radiation-induced effects (1), a central tenet of radiation biology, DNA damage occurs during or very shortly after irradiation of the nuclei in targeted cells, and the potential for biological consequences can be expressed within... Read More

December 11, 2015

EXPRESSION AND FUNCTION OF BACTERICIDAL/PERMEABILITY – INCREASING PROTEIN IN HUMAN GENITAL TRACT EPITHELIAL CELLS.

This study by researchers at Brigham and Women’s Hospital/Harvard Medical School demonstrated that MatTek’s EpiVaginal human cervico-vaginal tissue equivalent expresses bactericidal/permeability-increasing protein (BPI) and that this protein’s role in regulating bacterial colonization in the genital mucosa can be studied in... Read More

Reference Libraries

IMPROVED METHOD FOR THE GENERATION OF LONG LIVED AND FUNCTIONALLY ACTIVE DENDRITIC/LANGERHANS CELLS FROM CD34+ PROGENITOR CELLS.

LANGERHANS CELLS RELEASE PROSTAGLANDIN D2 IN RESPONSE TO NICOTINIC ACID.

IN VITRO DERIVED DENDRITIC CELLS TRANS-INFECT CD4 T CELLS PRIMARILY WITH SURFACE-BOUND HIV-1 VIRIONS.

STUDIES OF BYSTANDER EFFECTS IN ARTIFICIAL HUMAN 3D TISSUE SYSTEMS USING A MICROBEAM IRRADIATION.

EXPRESSION AND FUNCTION OF BACTERICIDAL/PERMEABILITY – INCREASING PROTEIN IN HUMAN GENITAL TRACT EPITHELIAL CELLS.

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