Reference Libraries

December 11, 2015

LANGERHANS CELLS RELEASE PROSTAGLANDIN D2 IN RESPONSE TO NICOTINIC ACID.

This study by researchers at Arena Pharmaceuticals demonstrated that MatTek’s Human Dendritic Cells can be used to identify the mechanism of a drug’s in vivo adverse side effects. Nicotinic acid, used for atherosclerosis treatment, has an adverse effect of skin... Read More

December 11, 2015

ACTIVATED CD34-DERIVED LANGERHANS CELLS MEDIATE TRANSINFECTION WITH HUMAN IMMUNODEFICIENCY VIRUS.

This study by researchers at Northwestern University’s Feinberg School of Medicine and the University of Illinois at Chicago College of Medicine demonstrated that it was possible to create and isolate a Langerhans Cells (LCs) subset of MatTek Human Dendritic Cells... Read More

December 11, 2015

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

EpiDerm (MatTek Co., MA) is a reconstituted human skin equivalent which exhibits morphological and growth characteristics similar to human skin. This model has previously been utilized to evaluate the cytotoxicity and irritant potential of various cosmetic and household products. In... Read More

December 11, 2015

THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.

The objective of this study was the pharmaco-toxicological understanding of the constituents of an authenticated herbal mixture. The mixture was prepared by maceration in ethanol and subsequent dilution to produce a topically applied lotion, for which the intended target conditions... Read More

December 11, 2015

THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.

This study by researchers at Genentech demonstrated that MatTek’s EpiDerm human skin tissue equivalent can be used to study the immunopathology of psoriasis. IL-19, IL-20, IL-22, IL-24, and IL-26 are members of the IL-10 family of cytokines that have been... Read More

Reference Libraries

LANGERHANS CELLS RELEASE PROSTAGLANDIN D2 IN RESPONSE TO NICOTINIC ACID.

ACTIVATED CD34-DERIVED LANGERHANS CELLS MEDIATE TRANSINFECTION WITH HUMAN IMMUNODEFICIENCY VIRUS.

RECONSTITUTED 3-DIMENSIONAL HUMAN SKIN AS A NOVEL IN VITRO MODEL FOR STUDIES OF CARCINOGENESIS.

THE DEVELOPMENT OF AN IN VITRO SCREENING STRATEGY FOR TOPICALLY APPLIED PRODUCTS.

THE EFFECTS OF IL-20 SUBFAMILY CYTOKINES ON RECONSTITUTED HUMAN EPIDERMIS SUGGEST POTENTIAL ROLES IN CUTANEOUS INNATE DEFENSE AND PATHOGENIC ADAPTIVE IMMUNITY IN PSORIASIS.

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