Reference Libraries

December 11, 2015

EYE AND SKIN IRRITATION IN 3-D HUMAN TISSUE CONSTRUCTS USING MTT AND ATP ENDPOINTS.

This study by scientists at Beauty Avenues and the Institute for In Vitro Sciences (IIVS) demonstrated that MatTek’s EpiDerm in vitro 3-D human skin tissue equivalent and EpiOcular in vitro 3-D human corneal tissue equivalent can be used, if/when necessary,... Read More

December 11, 2015

DEVELOPMENT OF A NEW IN VITRO GENETIC TOXICOLOGY MODEL USING RECONSTRUCTED HUMAN SKIN.

Choosing the Approach: • Procter & Gamble, a major cosmetics company, had excellent genetox personnel and expertise….and the idea to use a reconstructed skin model as a target tissue. • IIVS had extensive experience in using 3D skin models and... Read More

December 11, 2015

DI-PPG-2-MYRETH-10 ADIPATE REDUCES IRRITATION AND INFLAMMATION CAUSED BY COSMETIC PRODUCTS.

RL Goldemberg has stated that nonionic surfactants – particularly ethoxylated esters – act as counter irritants in amphoteric/anionic shampoo systems; several studies in our laboratories have demonstrated this desirable property (ethoxylated modified glycerides, and PEG-150 Pentaerythrityl Tetrastearate). In the search... Read More

December 11, 2015

The EpiOcular Eye Irritation Test (EIT) for Hazard Identification and Labelling of Eye Irritating Chemicals: Protocol Optimisation for Solid Materials and the Results after Extended Shipment

The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the human response to chemicals, cosmetics and other... Read More

December 11, 2015

MICROARRAY ANALYSIS OF GENE EXPRESSION FOLLOWING EXPOSURE TO SKIN IRRITANTS.

Understanding of the mechanistic basis of the human skin irritation response is key to the development of relevant in vitro test systems for the predictive identification of skin irritation hazards. Recent progress in genomic technologies means that tools for the... Read More

Reference Libraries

EYE AND SKIN IRRITATION IN 3-D HUMAN TISSUE CONSTRUCTS USING MTT AND ATP ENDPOINTS.

DEVELOPMENT OF A NEW IN VITRO GENETIC TOXICOLOGY MODEL USING RECONSTRUCTED HUMAN SKIN.

DI-PPG-2-MYRETH-10 ADIPATE REDUCES IRRITATION AND INFLAMMATION CAUSED BY COSMETIC PRODUCTS.

The EpiOcular Eye Irritation Test (EIT) for Hazard Identification and Labelling of Eye Irritating Chemicals: Protocol Optimisation for Solid Materials and the Results after Extended Shipment

MICROARRAY ANALYSIS OF GENE EXPRESSION FOLLOWING EXPOSURE TO SKIN IRRITANTS.

Get the latest