Reference Libraries

September 7, 2022

Anti-Glycation and Anti-Aging Properties of Resveratrol Derivatives in the in-vitro 3D Models of Human Skin

Purpose: Human skin undergoes modifications affecting its structural properties and barrier functions involved in protection against age-related damage. Glycation is a non-enzymatic reaction between macromolecules and sugars causing alterations to the elastic fibers and premature aging of the skin. Glycation... Read More

August 31, 2022

Correlation of In Vitro and In Vivo Skin Irritation Assays in Medical Devices: A Case Study

Biocompatibility testing is moving away from animal-based assays in favor of technologically advanced and reliable in silico and in vitro alternative approaches. While irritation has traditionally been assessed in a rabbit animal model, validated reconstructed human epidermis(RhE) models have been... Read More

August 24, 2022

Congeners-Specific Intestinal Absorption Of Microcystins In An In Vitro 3D Human Intestinal Epithelium: The Role Of Influx/Efflux Transporters

Microcystins constitute a group of over 200 variants and are increasingly considered as emerging toxins in food and feed safety, particularly with regards to sea-food and fish consumption. Toxicity of MCs is congener-specific, being characterised by different acute potencies, likely... Read More

August 24, 2022

Cytokine Release from Organotypic Human Oral Tissue Following Exposure to Oral Care Product Chemicals

Purpose: Measuring viability of a three-dimensional in vitro organotypic human oral tissue model has been suggested as an alternative test method to the oral mucosa irritation test of oral care products. The aim of this study was to investigate the... Read More

August 15, 2022

The soybean cultivar SCEL‑1 shows potent anti‑photoaging effects in a UV‑induced three‑dimensional human skin and hairless mouse model

Soybean (Glycine max) is one of the major sources of nutrition and is used as a raw material for food and as a source of feed for livestock. The efficacy of soybeans on skin health includes their ability to reduce... Read More