Reference Libraries

Currently, no alternative to the Draize eye test has been validated and ac-cepted by any regulatory body. The objective of this corporate-based programme was to formally validate the EpiOcular™ model’s ability to predict the eye irritation potential of surfactants and... Read More

This study compared five methods, the isolated rabbit eye (IRE), bovine cornea! opacity and permeability (BCOP), EpiOcular™, fluorescein leakage (FL) and neutral red release (NRR) assays, for predicting the eye irritation potential of hair-care formulations. Ten shampoo and seven conditioner... Read More

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Paraffin embedded, H&E stained histological cross-sections show the structure of EpiOcular closely parallels that of the... Read More

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Parafin embedded, H&E stained histology cross-sections show the structure of EpiOcular closely parallels that of the... Read More

The present project arose out of the proposals of a working group on reference standards established by ECVAM in 1997. The primary objective of this pilot study was to determine whether the current approach of using in vitro data to... Read More