Reference Libraries

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Paraffin embedded, H&E stained histological cross-sections show the structure of EpiOcular closely parallels that of the... Read More

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Paraffin embedded, H&E stained histological cross sections show the structure of EpiOcular closely parallels that of... Read More

Both EpiDerm™ and EpiOcular™ commercially available in vitro models for assessing the skin and eye irritation potential, respectively, of chemicals. The EpiDerm and EpiOcular tissue models are organotypic three-dimensional human skin and corneal analogues derived from human epidermal keratinocytes. Both... Read More

It has been reported that many in vitro test alternatives to the Draise eye irritation testing (Draize test) are able to evaluate irritation due to surfactants, but not organic solvents. We therefore examined an in vitro test using a 3-D... Read More

The present project arose out of the proposals of a working group on reference standards established by ECVAM in 1997. The primary objective of this pilot study was to determine whether the current approach of using in vitro data to... Read More