Reference Libraries

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Paraffin embedded, H&E stained histological cross sections show the structure of EpiOcular closely parallels that of... Read More

Currently, no alternative to the Draize eye test has been validated and ac-cepted by any regulatory body. The objective of this corporate-based programme was to formally validate the EpiOcular™ model’s ability to predict the eye irritation potential of surfactants and... Read More

Both EpiDerm™ and EpiOcular™ commercially available in vitro models for assessing the skin and eye irritation potential, respectively, of chemicals. The EpiDerm and EpiOcular tissue models are organotypic three-dimensional human skin and corneal analogues derived from human epidermal keratinocytes. Both... Read More

The EpiOcular™ tissue model (OCL-200) is an organotypic model of the human corneal epithelium (HCE) cultured from normal human keratinocytes using serum free medium. Paraffin embedded, H&E stained histological cross-sections show the structure of EpiOcular closely parallels that of the... Read More

The recently implemented 7th Amendment to the EU Cosmetics Directive and the EU REACH legislation have heightened the need for in vitro ocular test methods. To address this need, the EpiOcular™ eye irritation test (EpiOcular-EIT), which utilises the normal (non-transformed)... Read More