Reference Libraries

December 11, 2015

TESTING OF THE EPIOCULAR TISSUE MODEL FOLLOWING EXTENDED SHIPPING TIMES.

This study by scientists at Kurabo Industries (Japan) and MatTek Corp. demonstrated that MatTek’s EpiOcular in vitro human corneal tissue equivalent can be shipped long distances for extended shipping times and still meet intra- and inter-lot functional QC testing specifications.... Read More

December 11, 2015

INITIAL CHARACTERIZATION OF A NEW MODEL FOR OCULAR IRRITANCY TESTING.

A three dimensional, tissue culture construct, EpiDerm-SCA (EpiOcular™), based on neonatal foreskin-derived normal human epidermal keratinocytes (NHEK) is under development by MatTek Corporation. Cultured using serum free media in easily handled Millicell® CM (Millipore Corp.) cell culture inserts, the model... Read More

December 11, 2015

NON-ANIMAL METHODS FOR TOXICITY TESTING: EYE IRRITATION CORROSION.

One component in the safety assessment of many types of products is the evaluation of their potential to cause eye injury. Eye irritation is defined as “the production of changes in the eye following the application of test substance to... Read More

December 11, 2015

COLIPA PROGRAM ON OPTIMIZATION OF EXISTING IN VITRO EYE IRRITATION ASSAYS FOR ENTRY INTO FORMAL VALIDATION: TECHNOLOGY TRANSFER AND INTRA/INTER LABORATORY EVALUATION OF EPIOCULAR ASSAY FOR CHEMICALS.

This study by scientists at Mary Kay, Inc., COLIPA (European Cosmetics Association), Procter & Gamble Co. and MatTek Corp. demonstrated that MatTek’s EpiOcular in vitro human corneal tissue equivalent is a very accurate and reproducible in vitro model for the... Read More

December 11, 2015

PROSPECTIVE VALIDATION STUDY OF RECONSTRUCTED HUMAN TISSUE MODELS FOR EYE IRRITATION TESTING.

ECVAM/Colipa RhT test methods prospective validation study: The objective of the Eye Irritation Validation Study (EIVS) is to formally evaluate the scientific validity of the SkinEthicTM Human Corneal Epithelium (HCE) Short Exposure (SE), Long Exposure (LE) and test strategy and... Read More

Reference Libraries

TESTING OF THE EPIOCULAR TISSUE MODEL FOLLOWING EXTENDED SHIPPING TIMES.

INITIAL CHARACTERIZATION OF A NEW MODEL FOR OCULAR IRRITANCY TESTING.

NON-ANIMAL METHODS FOR TOXICITY TESTING: EYE IRRITATION CORROSION.

COLIPA PROGRAM ON OPTIMIZATION OF EXISTING IN VITRO EYE IRRITATION ASSAYS FOR ENTRY INTO FORMAL VALIDATION: TECHNOLOGY TRANSFER AND INTRA/INTER LABORATORY EVALUATION OF EPIOCULAR ASSAY FOR CHEMICALS.

PROSPECTIVE VALIDATION STUDY OF RECONSTRUCTED HUMAN TISSUE MODELS FOR EYE IRRITATION TESTING.

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