Reference Libraries

December 11, 2015

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

Simple, safe and effective permeability enhancers are crucial for successful non-invasive drug delivery methods. We seek local permeability augmentation mechanisms for integration into passive or active architectures in order to enable novel therapeutic delivery routes of the target drug while... Read More

December 11, 2015

BIOCONVERSION OF NALTREXONE AND ITS 3-O-ALKYL-ESTER PRODRUGS IN A HUMAN SKIN EQUIVALENT.

This study by scientists at the University of Kentucky College of Pharmacy and MatTek Corp. demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent can be used as an alternative experimental system to human skin for the prediction of... Read More

December 11, 2015

RECONSTRUCTION OF NEW ORGANOTYPIC 3D HUMAN SMALL INTESTINE TISSUE MODEL FOR DRUG SAFETY AND TOXICITY.

The epithelial lining of the gastrointestinal (GI) tract is a gatekeeper for entry of orally ingested nutrients and xenobiotics including medicaments. The small intestine has a well organized structure containing proliferative cells which migrate along the crypt-villi axis and differentiate... Read More

December 11, 2015

DAS181, A SIALIDASE FUSION PROTEIN, PROTECTS HUMAN AIRWAY EPITHELIUM AGAINST INFLUENZA VIRUS INFECTION: AN IN VITRO PHARMACODYNAMIC ANALYSIS.

This study by researchers at NexBio and the University of Hong Kong demonstrated that MatTek’s EpiAirway in vitro 3-D human tracheal/bronchial tissue equivalent can be used to model the pharmacodynamics of a new drug formulation that inhibits influenza virus infection.... Read More

December 11, 2015

RETAINING CELL INTEGRITY DURING ORGANOTYPIC MODEL VIABILITY ASSAYS: ALTERNATIVES TO MTT.

This study by researchers at the State University of New York (SUNY) at Stony Brook documents the effort to the develop an alternative tissue viability endpoint analysis using a non-lytic agent (MTS, Alamar Blue or CalceinAM) in place of the... Read More

Reference Libraries

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

BIOCONVERSION OF NALTREXONE AND ITS 3-O-ALKYL-ESTER PRODRUGS IN A HUMAN SKIN EQUIVALENT.

RECONSTRUCTION OF NEW ORGANOTYPIC 3D HUMAN SMALL INTESTINE TISSUE MODEL FOR DRUG SAFETY AND TOXICITY.

DAS181, A SIALIDASE FUSION PROTEIN, PROTECTS HUMAN AIRWAY EPITHELIUM AGAINST INFLUENZA VIRUS INFECTION: AN IN VITRO PHARMACODYNAMIC ANALYSIS.

RETAINING CELL INTEGRITY DURING ORGANOTYPIC MODEL VIABILITY ASSAYS: ALTERNATIVES TO MTT.

Get the latest