Reference Libraries

December 11, 2015

EVALUATION OF RECONSTITUTED HUMAN VAGINAL EPITHELIUM AS A MODEL FOR DRUG DELIVERY OF FLUCONAZOLE GEL FOR TREATING VULVOVAGINAL CANDIDIASIS.

Purpose: The goal of this project performed by researchers at the Massachusetts College of Pharmacy and Health Sciences was to evaluate the use of EpiVaginal, a reconstituted human vaginal epithelium, as a model for penetration for an antifungal gel containing... Read More

December 11, 2015

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

Simple, safe and effective permeability enhancers are crucial for successful non-invasive drug delivery methods. We seek local permeability augmentation mechanisms for integration into passive or active architectures in order to enable novel therapeutic delivery routes of the target drug while... Read More

December 11, 2015

THE EFFICACY OF ECHINACEA IN A 3-D TISSUE MODEL OF HUMAN AIRWAY EPITHELIUM.

This study by researchers at the University of British Columbia and A. Vogel Bioforce AG demonstrated that MatTek’s EpiAirway in vitro 3-D human tracheal/bronchial tissue equivalent can be infected with rhinovirus type 1A (RV1A) and then used to evaluate the... Read More

December 11, 2015

NALTREXONE AND NALTREXONE-3-O-VALERATE DIFFUSION AND BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.

Transdermal naltrexone delivery may help improve patient compliance in the treatment of narcotic dependence and alcoholism. Lipophilic alkyl ester prodrugs increase the delivery rate of naltrexone across human surgical waste skin in vitro. Human skin equivalent models can be useful... Read More

December 11, 2015

NOVEL 3D HUMAN SMALL INTESTINAL TISSUE MODEL (EPIINESTINAL™ ) TO ASSESS DRUG PERMEATION & INFLAMMATION

Purpose: Drug transport and permeability across the small intestine (SMI) is a key parameter for determining bioavailability of orally administered drugs. The currently available in vitro models are highly dependent on immortalized cell lines (e.g. Caco-2) and have significant deficiencies... Read More

Reference Libraries

EVALUATION OF RECONSTITUTED HUMAN VAGINAL EPITHELIUM AS A MODEL FOR DRUG DELIVERY OF FLUCONAZOLE GEL FOR TREATING VULVOVAGINAL CANDIDIASIS.

HYDROGEN PEROXIDE MEDIATED TRANSVAGINAL DRUG DELIVERY.

THE EFFICACY OF ECHINACEA IN A 3-D TISSUE MODEL OF HUMAN AIRWAY EPITHELIUM.

NALTREXONE AND NALTREXONE-3-O-VALERATE DIFFUSION AND BIOCONVERSION IN A HUMAN EPIDERMIS EQUIVALENT.

NOVEL 3D HUMAN SMALL INTESTINAL TISSUE MODEL (EPIINESTINAL™ ) TO ASSESS DRUG PERMEATION & INFLAMMATION

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