Reference Libraries

December 11, 2015

EXPRESSION OF STRATUM CORNEUM LIPID PATHWAYS IN HUMAN SKIN EQUIVALENT CULTURES.

This study by scientists at Procter & Gamble Beauty demonstrated that gene pathways involved in stratum corneum lipid formation are expressed in MatTek’s EpiDermFT full-thickness in vitro 3-D human skin tissue equivalent, suggesting that ths culture system is an appropriate... Read More

December 11, 2015

XENOBIOTIC METABOLISM GENE EXPRESSION IN THE EPIDERM™ IN VITRO 3D HUMAN EPIDERMIS MODEL COMPARED TO HUMAN SKIN.

There is an urgent need to validate in vitro human skin models for use in safety testing. An important component of validation is characterizing the metabolizing capacity of these models. We report comparison of the expression of 139 genes encoding... Read More

December 11, 2015

Airway Epithelial Injury, Fibroblast Changes and Cytokine/Chemokine Profiles Induced by Exposure of Human EpiAirway-FT Tissues to Diacetyl Vapors

Inhalation exposure to diacetyl (DA) vapors in artificial butter flavorings has been associated with the development of obliterative bronchiolitis (OB) in microwave popcorn factory workers. Inhalation of DA vapors has also been shown to cause OB-like lesions in rats. EpiAirway-full... Read More

December 11, 2015

CHARACTERIZATION OF THE RETROCYCLIN ANALOGUE RC-101 AS A PREVENTATIVE OF STAPHYLOCOCCUS AUREUS NASAL COLONIZATION.

Nasal colonization of Staphylococcus aureus is a risk factor for pathogenic autoinfection, particularly in postoperative patients and the immunocompromised. As such, standardized preoperative nasal decolonization of S. aureus has become a major consideration for the prevention of nosocomial infection. However,... Read More

December 11, 2015

EARLY HOST RESPONSES OF SEASONAL AND PANDEMIC INFLUENZA A VIRUSES IN PRIMARY WELL-DIFFERENTIATED HUMAN LUNG EPITHELIAL CELLS

Replication, cell tropism and the magnitude of the host’s antiviral immune response each contribute to the resulting pathogenicity of influenza A viruses (IAV) in humans. In contrast to seasonal IAV in human cases, the 2009 H1N1 pandemic IAV (H1N1pdm) shows... Read More

Reference Libraries

EXPRESSION OF STRATUM CORNEUM LIPID PATHWAYS IN HUMAN SKIN EQUIVALENT CULTURES.

XENOBIOTIC METABOLISM GENE EXPRESSION IN THE EPIDERM™ IN VITRO 3D HUMAN EPIDERMIS MODEL COMPARED TO HUMAN SKIN.

Airway Epithelial Injury, Fibroblast Changes and Cytokine/Chemokine Profiles Induced by Exposure of Human EpiAirway-FT Tissues to Diacetyl Vapors

CHARACTERIZATION OF THE RETROCYCLIN ANALOGUE RC-101 AS A PREVENTATIVE OF STAPHYLOCOCCUS AUREUS NASAL COLONIZATION.

EARLY HOST RESPONSES OF SEASONAL AND PANDEMIC INFLUENZA A VIRUSES IN PRIMARY WELL-DIFFERENTIATED HUMAN LUNG EPITHELIAL CELLS

Get the latest