Reference Libraries

December 11, 2015

EXPRESSION OF STRATUM CORNEUM LIPID PATHWAYS IN HUMAN SKIN EQUIVALENT CULTURES.

This study by scientists at Procter & Gamble Beauty demonstrated that gene pathways involved in stratum corneum lipid formation are expressed in MatTek’s EpiDermFT full-thickness in vitro 3-D human skin tissue equivalent, suggesting that ths culture system is an appropriate... Read More

December 11, 2015

SULFUR MUSTARD VAPOR EFFECTS ON DIFFERENTIATED HUMAN LUNG CELLS.

Context: sulfur mustard (SM) causes skin blistering and long-term pulmonary dysfunction. Its adverse effects have been studied in battlefield-exposed humans, but lack of knowledge regarding confounding factors makes interpretation challenging. Animal studies are critical to understanding mechanisms, but differences between... Read More

December 11, 2015

EFFECT OF CYCLODEXTRINS ON THE COMPLEXATION AND NASAL PERMEATION OF MELATONIN.

The inclusion complexation of melatonin (MT) with modified cyclodextrins (CDs) was studied with an objective of improving the solubility and nasal absorption of MT. The formation of inclusion complex of MT with Hydroxypropyl âCD (HPâCD) and randomly rnethylated ÂCD (RMâCD)... Read More

December 11, 2015

CHARACTERIZATION OF THE EFFECT OF URINE ON MECHANICALLY INDUCED SKIN DAMAGE.

As stated in the “Conclusions” section, the main experiment in this study by researchers at Eindhoven University of Technology was performed to determine whether urine makes the skin more susceptible for mechanical loading, and that to make this determination, an... Read More

December 11, 2015

XENOBIOTIC METABOLISM GENE EXPRESSION IN THE EPIDERM™ IN VITRO 3D HUMAN EPIDERMIS MODEL COMPARED TO HUMAN SKIN.

There is an urgent need to validate in vitro human skin models for use in safety testing. An important component of validation is characterizing the metabolizing capacity of these models. We report comparison of the expression of 139 genes encoding... Read More

Reference Libraries

EXPRESSION OF STRATUM CORNEUM LIPID PATHWAYS IN HUMAN SKIN EQUIVALENT CULTURES.

SULFUR MUSTARD VAPOR EFFECTS ON DIFFERENTIATED HUMAN LUNG CELLS.

EFFECT OF CYCLODEXTRINS ON THE COMPLEXATION AND NASAL PERMEATION OF MELATONIN.

CHARACTERIZATION OF THE EFFECT OF URINE ON MECHANICALLY INDUCED SKIN DAMAGE.

XENOBIOTIC METABOLISM GENE EXPRESSION IN THE EPIDERM™ IN VITRO 3D HUMAN EPIDERMIS MODEL COMPARED TO HUMAN SKIN.

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