Reference Libraries

December 11, 2015

CD137/CD137L EXPRESSION AND SIGNALING IN IN VITRO MODELS OF HUMAN AIRWAY EPITHELIUM, DENDRITIC CELLS AND T-CELLS.

This study by scientists at MatTek Corp. demonstrated that MatTek’s EpiAirway in vitro human airway tissue model and MatTek’s Human Dendritic Cells are excellent in vitro models for studying the signaling of CD137, a potent T-cell co-stimulatory molecule related to... Read More

December 11, 2015

CELL TYPE-DEPENDENT GENE TRANSCRIPTION PROFILE IN A THREE-DIMENSIONAL HUMAN SKIN TISSUE MODEL EXPOSED TO LOW DOSES OF IONIZING RADIATION: IMPLICATIONS FOR MEDICAL EXPOSURES.

The concern over possible health risks from exposures to low doses of ionizing radiation has been driven largely by the increase in medical exposures, the routine implementation of X-ray backscatter devices for airport security screening, and, most recently, the nuclear... Read More

December 11, 2015

A NEW DECORIN-LIKE TETRAPEPTIDE FOR OPTIMAL ORGANIZATION OF COLLAGEN FIBRES.

Decorin interacts with collagen via its protein core and influences collagen fibrillogenesis, thus regulating excessive bundle-like aggregation of collagen. As skin ages, there is lack of functional decorin, which results in disrupted collagen fibres and in a reduction in the... Read More

December 11, 2015

SIMULATION OF ELECTRON-BEAM IRRADIATION OF SKIN TISSUE MODEL.

Monte Carlo simulation of electrons stopping in liquid water was used to model the penetration and quality of electron-beam irradiation incident on the full-thickness EpiDermTM skin model (EpiDermFTTM MatTek, Ashland, VA). This 3D tissue model has a fully developed basement... Read More

December 11, 2015

EXPRESSION OF 15-LIPOXYGENASE-2 IN THE EPIAIRWAY™ IN VITRO HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL: REGULATION BY TNF-α AND INF-γ.

15-Hydroxyeicosatetraenoic acid (15[S]-HETE) is the predominate arachidonic acid (AA) metabolite produced by human tracheal/bronchial tissue. This product of the 15-lipoxygenase (15-LOX) enzyme is believed to play a significant role in human airway inflammation and respiratory diseases including cystic fibrosis and... Read More

Reference Libraries

CD137/CD137L EXPRESSION AND SIGNALING IN IN VITRO MODELS OF HUMAN AIRWAY EPITHELIUM, DENDRITIC CELLS AND T-CELLS.

CELL TYPE-DEPENDENT GENE TRANSCRIPTION PROFILE IN A THREE-DIMENSIONAL HUMAN SKIN TISSUE MODEL EXPOSED TO LOW DOSES OF IONIZING RADIATION: IMPLICATIONS FOR MEDICAL EXPOSURES.

A NEW DECORIN-LIKE TETRAPEPTIDE FOR OPTIMAL ORGANIZATION OF COLLAGEN FIBRES.

SIMULATION OF ELECTRON-BEAM IRRADIATION OF SKIN TISSUE MODEL.

EXPRESSION OF 15-LIPOXYGENASE-2 IN THE EPIAIRWAY™ IN VITRO HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL: REGULATION BY TNF-α AND INF-γ.

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