Reference Libraries

December 11, 2015

EPSTEIN-BARR VIRUS ENCODED DUTPASE CONTAINING EXOSOMES MODULATE INNATE AND ADAPTIVE IMMUNE RESPONSES IN HUMAN DENDRITIC CELLS AND PERIPHERAL BLOOD MONONUCLEAR CELLS.

We have recently demonstrated that Epstein-Barr virus (EBV)-encoded deoxyuridine triphosphate nucleotidohydrolase (dUTPase) modulates innate immunity in human primary monocyte-derived macrophages through toll-like receptor (TLR) 2 leading to NF-KB activation and the production of pro-inflammatory cytokines. Our previous depletion studies indicated... Read More