Reference Libraries

December 11, 2015

GENE EXPRESSION ANALYSIS OF DENDRITIC/LANGERHANS CELLS AND LANGERHANS CELL HISTIOCYTOSIS.

This study by researchers in the departments of Pathology and Laboratory Medicine, and Pediatric Oncology at the University of Groningen demonstrated that MatTek’s Human Langerhans/Dendritic Cells are an excellent in vitro model for studying the gene expression of Langerhans cell... Read More

December 11, 2015

SKIN SCIENCE: THE USE OF GENOMICS TOOLS IN SKIN CARE.

This study by scientists at Genemarkers LLC demonstrated that MatTek’s EpiDermFT full-thickness in vitro human skin tissue equivalent can be used to identify the human genes activated when anti-aging and anti-wrinkle cosmeceutical products are applied to the apical surface. Elina... Read More

December 11, 2015

TUMOR NECROSIS FACTOR ALPHA (TNFα) INDUCTION OF THYMUS AND ACTIVATION REGULATED CHEMOKINE (TARC) EXPRESSION IS MEDIATED BY 15-LIPOXYGENASE 15-(LOX)-2 IN THE EPIAIRWAY™ HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL.

RATIONALE: T-Helper 2-type (TH2) T cells play a predominant role in human airway inflammation and asthma. TARC, a specific chemoattractant for TH2 cells, is induced by TNFα treatment of human airway cells, however, the cellular pathways involved in mediating TARC... Read More

December 11, 2015

CIGARETTE SMOKE ALTERS TISSUE INHIBITOR OF METALLOPROTEINASE 1 AND MATRIX METALLOPROTEINASE 9 LEVELS IN THE BASOLATERAL SECRETIONS OF HUMAN ASTHMATIC BRONCHIAL EPITHELIUM IN VITRO.

Background: Asthma, a major cause of chronic lung disease worldwide, has increased in prevalence in all age and ethnic groups, particularly in urban areas where cigarette smoking is common. Cigarette smoke (CS) significantly impacts the development of asthma and is... Read More

December 11, 2015

APPLICATION OF ORGANOTYPIC IN VITRO HUMAN CELL CULTURE MODELS FOR RESEARCH AND DEVELOPMENT OF INHALATION PHARMACEUTICAL FORMULATIONS TARGETING THE PROXIMAL AIRWAYS.

Delivery of pharmaceuticals via inhalation is a potentially useful alternative to intravenous injection for drugs that are unstable or poorly absorbed after oral administration; for chronic disease conditions that require frequent administration: or therapeutics for which the airways are the... Read More

Reference Libraries

GENE EXPRESSION ANALYSIS OF DENDRITIC/LANGERHANS CELLS AND LANGERHANS CELL HISTIOCYTOSIS.

SKIN SCIENCE: THE USE OF GENOMICS TOOLS IN SKIN CARE.

TUMOR NECROSIS FACTOR ALPHA (TNFα) INDUCTION OF THYMUS AND ACTIVATION REGULATED CHEMOKINE (TARC) EXPRESSION IS MEDIATED BY 15-LIPOXYGENASE 15-(LOX)-2 IN THE EPIAIRWAY™ HUMAN TRACHEAL/BRONCHIAL EPITHELIAL MODEL.

CIGARETTE SMOKE ALTERS TISSUE INHIBITOR OF METALLOPROTEINASE 1 AND MATRIX METALLOPROTEINASE 9 LEVELS IN THE BASOLATERAL SECRETIONS OF HUMAN ASTHMATIC BRONCHIAL EPITHELIUM IN VITRO.

APPLICATION OF ORGANOTYPIC IN VITRO HUMAN CELL CULTURE MODELS FOR RESEARCH AND DEVELOPMENT OF INHALATION PHARMACEUTICAL FORMULATIONS TARGETING THE PROXIMAL AIRWAYS.

Get the latest