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December 11, 2015

BIOCHEMICAL INVESTIGATION AND GENE ANALYSIS OF EQUOL: A PLANT AND SOY-DERIVED ISOFLAVONOID WITH ANTIAGING AND ANTIOXIDANT PROPERTIES WITH POTENTIAL HUMAN SKIN APPLICATIONS.

The purpose of this study was to investigate the effects of equol, a plant and intestinal flora derived isoflavonoid molecule on the expression of skin genes and proteins using human dermal models. As equol has been shown to mimic 17β-estradiol... Read More

December 11, 2015

DIFFERENTIAL MODULATION OF ECM COMPONENTS AND GFR BY RETINOIC ACID AND A PHYSIOLOGICALLY BALANCED GF FORMULATION.

Overall appearance of skin is a combination of health, ethnicity, lifestyle and age, which determine skin color, texture, firmness and smoothness. Uneven color, rough, lax and wrinkled skin are associated with aged skin. Microscopically, aged skin has an atrophic epidermis,... Read More

December 11, 2015

PROTECTION AND REPAIR OF SKIN DAMAGE FROM ENVIRONMENTAL AGGRESSORS.

There is an increasing awareness that environmental factors, such as UV, cigarette smoke, pollution, and extreme temperatures can lead to skin aging. The mechanisms underlying this extrinsic aging effect remain uncertain. Previous studies showed that one of the negative actions... Read More

December 11, 2015

BY IL-1 SIGNALING, MONOCYTE-DERIVED CELLS DRAMATICALLY ENHANCE THE EPIDERMAL ANTIMICROBIAL RESPONSE TO LIPOPOLYSACCHARIDE.

Epithelia react to microbial pathogens by mounting a defensive response that includes the production of antimicrobial peptides. In this study, we show that, in human epidermal cultures, Escherichia coli LPS was a very weak direct inducer of human β-defensin (HBD)-2... Read More

December 11, 2015

EVALUATION OF COSMETIC INGREDIENTS IN TISSUE ENGINEERED HUMAN SKIN IN VITRO.

This study by scientists at Procter & Gamble demonstrated that MatTek’s MelanoDerm and EpiDermFT in vitro human skin equivalent tissues are useful tools in understanding how compounds used in anti-aging cosmetic products (“cosmeceuticals”) like N-acetyl glucosamine and niacinamide affect production... Read More

Reference Libraries

BIOCHEMICAL INVESTIGATION AND GENE ANALYSIS OF EQUOL: A PLANT AND SOY-DERIVED ISOFLAVONOID WITH ANTIAGING AND ANTIOXIDANT PROPERTIES WITH POTENTIAL HUMAN SKIN APPLICATIONS.

DIFFERENTIAL MODULATION OF ECM COMPONENTS AND GFR BY RETINOIC ACID AND A PHYSIOLOGICALLY BALANCED GF FORMULATION.

PROTECTION AND REPAIR OF SKIN DAMAGE FROM ENVIRONMENTAL AGGRESSORS.

BY IL-1 SIGNALING, MONOCYTE-DERIVED CELLS DRAMATICALLY ENHANCE THE EPIDERMAL ANTIMICROBIAL RESPONSE TO LIPOPOLYSACCHARIDE.

EVALUATION OF COSMETIC INGREDIENTS IN TISSUE ENGINEERED HUMAN SKIN IN VITRO.

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