Reference Libraries

December 11, 2015

CHARACTERIZATION AND EVALUATION OF CD34+ GENERATED LANGERHANS CELLS FOR TISSUE ENGINEERING.

Specialized antigen-presenting cells (APC), particularly Langerhans cells (LC) residing in the skin, mucosa, and lymphoid tissues play a key role in sensitization and other immunological reactions of the body. However, difficulty in harvesting, short survival time in culture, and variability... Read More

December 11, 2015

A PLASMACYTOID DENDRITIC CELL (CD123+/CD11c−) BASED ASSAY SYSTEM TO PREDICT CONTACT ALLERGENICITY OF CHEMICALS.

This study by scientists at MatTek Corp. demonstrated that CD86 expression in the plasmacytoid Dendritic Cell (pDC) fraction of MatTek’s Human Dendritic Cells is a sensitive and specific indicator of contact allergenicity, and that an assay method utilizing normal human... Read More

December 11, 2015

HARVEST, PROLIFERATION, AND FUNCTIONAL TESTING OF HUMAN DENDRITIC CELLS.

Purpose: Difficulty in harvesting large numbers of cells, short survival time, and rapid phenotypic changes in culture have prevented the widespread use of human dendritic cells (DC) for many fundamental studies applicable to the initial stages of pharmaceutical discovery and... Read More

December 11, 2015

CYTOKINE RESPONSE OF THE EPIDERM SKIN MODEL TO TOPICALLY APPLIED IRRITANTS AND TOXICANTS.

EpiDerm™, MatTek Corporation’s in vitro reproduction of the human epidermis provides a convenient way in which toxicity and irritation potential of chemicals and physical stresses can be assessed. Derived from single strains of human keratinocytes, the model contains layers of... Read More

December 11, 2015

CYTOKINE AND LIPID MEDIATOR RELEASE FROM IN VITRO SKIN MODELS FOLLOWING DETERGENT TREATMENT OR PHYSICAL WOUNDING.

The purpose of the present work is to characterize two in vitro skin mod-els with regard to release of inflammatory cytokines and lipids under basal conditions and following chemical or physical damage. The two models evaluated are Skin2 (Advanced Tissue... Read More

Reference Libraries

CHARACTERIZATION AND EVALUATION OF CD34+ GENERATED LANGERHANS CELLS FOR TISSUE ENGINEERING.

A PLASMACYTOID DENDRITIC CELL (CD123+/CD11c−) BASED ASSAY SYSTEM TO PREDICT CONTACT ALLERGENICITY OF CHEMICALS.

HARVEST, PROLIFERATION, AND FUNCTIONAL TESTING OF HUMAN DENDRITIC CELLS.

CYTOKINE RESPONSE OF THE EPIDERM SKIN MODEL TO TOPICALLY APPLIED IRRITANTS AND TOXICANTS.

CYTOKINE AND LIPID MEDIATOR RELEASE FROM IN VITRO SKIN MODELS FOLLOWING DETERGENT TREATMENT OR PHYSICAL WOUNDING.

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