Reference Libraries

Human dendritic cells have been used to evaluate the allergenicity potential of chemicals and develop alternatives to existing animal models utilized throughout industry to monitor products for contact sensitization. Development of such non-animal alternative assay systems for hazard assessment directly... Read More

Dendritic cells (DC) residing in the skin, mucosa, and lymphoid tissues play a key role in sensitization and viral infection. However, difficulty in harvesting, short survival time in culture, rapid phenotypic changes, and variability in cytokine release patterns by cultured... Read More

This study by MatTek scientists demonstrated that MatTek’s Human Dendritic Cells are an excellent in vitro model for use in a wide variety of studies related to allergenicity, microbial infection and transmission, neutralizing antibodies and anti-microbial agents, antigen capture and... Read More