Reference Libraries

December 11, 2015

PLASMACYTOID DENDRITIC CELLS AS A TOOL FOR TESTING ALLERGENICITY OF CHEMICALS.

This study by MatTek Corp. scientists demonstrated that MatTek’s Human Dendritic Cells (DCs) contain both plasmacytoid DCs (pDC) and myeloid DCs (mDC), that they can be separated into those 2 cell populations, and that MatTek pDCs can be used to... Read More

December 11, 2015

EVALUATION OF PLASMACYTOID DENDRITIC CELL-BASED ASSAY TO DETERMINE CHEMICAL ALLERGENICITY.

Human dendritic cells have been used to evaluate the allergenicity potential of chemicals and develop alternatives to existing animal models utilized throughout industry to monitor products for contact sensitization. Development of such non-animal alternative assay systems for hazard assessment directly... Read More

December 11, 2015

COMPARISON OF AN IN VITRO HUMAN SKIN EQUIVALENT MODEL TO NORMAL HUMAN SKIN FOR DERMATOLOGICAL RESEARCH.

EpiDerm, an in vitro human skin equivalent (HSE), was compared to normal human breast skin (NHS) to morphologically and biochemically assess its feasibility for dermatological research. Intralot and interlot variability was studied in day 0, 1, 2, and 3 in... Read More

December 11, 2015

RECONSTRUCTED EPIDERMIS AND FULL-THICKNESS SKIN FOR ABSORPTION TESTING: INFLUENCE OF THE VEHICLES USED ON STEROID PERMEATION.

This study by researchers at the Free University of Berlin demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent and EpiDermFT full-thickness in vitro human skin tissue equivalent can be used in the development of topical dermatics and for... Read More

December 11, 2015

LOCALIZATION OF β-GLUCOCEREBROSIDASE ACTIVITY IN MAMMALIAN EPIDERMIS BY IN SITU ZYMOGRAPHY.

A critical, late step in epidermal barrier formation is the transformation of secreted lamellar body contents into mature extracellular lamellar unit structures. Although previous studies have demonstrated a crucial role for the enzyme β-glucocerebrosidase (GlcCer’ase) in the final steps of... Read More

Reference Libraries

PLASMACYTOID DENDRITIC CELLS AS A TOOL FOR TESTING ALLERGENICITY OF CHEMICALS.

EVALUATION OF PLASMACYTOID DENDRITIC CELL-BASED ASSAY TO DETERMINE CHEMICAL ALLERGENICITY.

COMPARISON OF AN IN VITRO HUMAN SKIN EQUIVALENT MODEL TO NORMAL HUMAN SKIN FOR DERMATOLOGICAL RESEARCH.

RECONSTRUCTED EPIDERMIS AND FULL-THICKNESS SKIN FOR ABSORPTION TESTING: INFLUENCE OF THE VEHICLES USED ON STEROID PERMEATION.

LOCALIZATION OF β-GLUCOCEREBROSIDASE ACTIVITY IN MAMMALIAN EPIDERMIS BY IN SITU ZYMOGRAPHY.

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