Reference Libraries

December 11, 2015

A PLASMACYTOID DENDRITIC CELL (CD123+/CD11c−) BASED ASSAY SYSTEM TO PREDICT CONTACT ALLERGENICITY OF CHEMICALS.

This study by scientists at MatTek Corp. demonstrated that CD86 expression in the plasmacytoid Dendritic Cell (pDC) fraction of MatTek’s Human Dendritic Cells is a sensitive and specific indicator of contact allergenicity, and that an assay method utilizing normal human... Read More

December 11, 2015

CYTOKINE AND LIPID MEDIATOR RELEASE FROM IN VITRO SKIN MODELS FOLLOWING DETERGENT TREATMENT OR PHYSICAL WOUNDING.

The purpose of the present work is to characterize two in vitro skin mod-els with regard to release of inflammatory cytokines and lipids under basal conditions and following chemical or physical damage. The two models evaluated are Skin2 (Advanced Tissue... Read More

December 11, 2015

PLASMACYTOID DENDRITIC CELL-BASED ASSAY AS AN IN VITRO ALTERNATIVE FOR CHEMICAL ALLERGENICITY SCREENING.

Human dendritic cells (DC) have been used as an alternative to existing animal models utilized throughout industry to monitor products for contact sensitization. Such methods are necessary to comply with the ban on animal testing imposed by the Cosmetics Directive... Read More

December 11, 2015

IMPROVED RESPONSIVENESS OF LANGERHANS / DENDRITIC CELLS TO ALLERGENS.

Langerhans cells (LC) are immature dendritic cells (DC) that are highly specialized antigen-presenting cells (APC) located in the skin, mucosa, and lymphoid tissues. LC play a key role in the induction phase of contact allergenicity, and hence it may be... Read More

December 11, 2015

CHARACTERIZATION AND EVALUATION OF CD34+ GENERATED LANGERHANS CELLS FOR TISSUE ENGINEERING.

Specialized antigen-presenting cells (APC), particularly Langerhans cells (LC) residing in the skin, mucosa, and lymphoid tissues play a key role in sensitization and other immunological reactions of the body. However, difficulty in harvesting, short survival time in culture, and variability... Read More

Reference Libraries

A PLASMACYTOID DENDRITIC CELL (CD123+/CD11c−) BASED ASSAY SYSTEM TO PREDICT CONTACT ALLERGENICITY OF CHEMICALS.

CYTOKINE AND LIPID MEDIATOR RELEASE FROM IN VITRO SKIN MODELS FOLLOWING DETERGENT TREATMENT OR PHYSICAL WOUNDING.

PLASMACYTOID DENDRITIC CELL-BASED ASSAY AS AN IN VITRO ALTERNATIVE FOR CHEMICAL ALLERGENICITY SCREENING.

IMPROVED RESPONSIVENESS OF LANGERHANS / DENDRITIC CELLS TO ALLERGENS.

CHARACTERIZATION AND EVALUATION OF CD34+ GENERATED LANGERHANS CELLS FOR TISSUE ENGINEERING.

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