Reference Libraries

EpiDerm, an in vitro human skin equivalent (HSE), was compared to normal human breast skin (NHS) to morphologically and biochemically assess its feasibility for dermatological research. Intralot and interlot variability was studied in day 0, 1, 2, and 3 in... Read More

Physiological structures associated with iontophoretic paths in hairless mouse skin and two cultured skin models (“EpiDerm” by Mattek, Corp., and “SKIN” by Advanced Tissue Sciences, Inc.) are reported. Visualization of ionic paths at current densities between 20 and 100 uA/cm2... Read More

Zinc sulfate monohydrate is a widely used agent in the pharmaceutical industry. It can be applied on the skin in the form of a solution, ointment, or lotion, and recently in the form of non-woven fabrics impregnated with zinc sulfate... Read More

The study aimed at evaluating tissue architecture and quality of the permeability barrier in commercially available reconstructed human skin models; EpiDerm™, SkinEthic™ and Episkin™ in comparison to native tissue. For this purpose, tissue architecture was examined by electron microscopy and... Read More

A model of the human epidermis, EpiDerm, cultured from neonatal, nor-mal human epidermal keratinocytes has been sold commercially by MatTek Cor-poration since April 1993. Using serum free media, weekly batches of EpiDerm are produced and shipped for dermal irritancy, product... Read More