Reference Libraries

August 26, 2020

Functional Characterization and Permeation Studies of Lyophilised Thiolated Chitosan Xerogels for Buccal Delivery of Insulin

Stable and mucoadhesive, lyophilised, thiolated chitosan xerogels, loaded with insulin for buccal mucosa delivery, in place of the currently used parenteral route have been developed. The xerogels were backed with impervious ethylcellulose laminate to ensure unidirectional release and also loaded... Read More

August 26, 2020

Denture-associated biofilm infection in three-dimensional oral mucosal tissue models

Purpose. In vitro analyses of virulence, pathogenicity and associated host cell responses are important components in the study of biofilm infections. The Candida-related infection, denture-associated oral candidosis, affects up to 60% of denture wearers and manifests as inflammation of palatal... Read More

August 25, 2020

Evaluating the Inflammatory and Genotoxic Effects of Smokeless Tobacco Using a Human Organotypic Model of Oral Epithelium

In addition to the well-known effects of tobacco use on the causation of lung and cardiovascular disease, tobacco use is also implicated as a major cause of oral cavity disease that leads to thousands of deaths per year. Snus, a... Read More

August 25, 2020

A heat-stable microparticle platform for oral micronutrient delivery

Micronutrient deficiencies affect up to 2 billion people and are the leading cause of cognitive and physical disorders in the developing world. Food fortification is effective in treating micronutrient deficiencies; however, its global implementation has been limited by technical challenges... Read More

August 24, 2020

Oxidative stress in corneal injuries of different origin: Utilization of 3D human corneal epithelial tissue model

The purpose of the current work was to utilize a three dimensional (3D) corneal epithelial tissue model to study dry eye disease and oxidative stress-related corneal epithelial injuries for the advancement of ocular therapeutics. Air-liquid interface cultures of normal human... Read More