Reference Libraries

August 4, 2017

In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

RHE skin model systems can provide very valuable early indications of therapeutic candidate biology, pharmacology, and toxicity.

July 20, 2017

Cytotoxicity of copper (II) oxide nanoparticles in rat and human intestinal cell models

The objective of this study was to assess the cytotoxic effects of CuO NPs (size <50 nm) in rat and human intestinal cells.

July 20, 2017

In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response

In vitro systems are established for the preclinical assessment of skin irritation potential and alternative methods to the Draize rabbit test.

July 20, 2017

Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

The OECD TG 492 EpiOcular test method allows identifying chemicals that neither induce eye irritation nor serious eye damage.

November 14, 2016

Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures

Cigarette smoke (CS) has been reported to increase predisposition to oral cancer and is also recognized as a risk factor for many conditions including periodontal diseases, gingivitis, and other benign mucosal disorders. Smoking cessation remains the most effective approach for minimizing the risk of... Read More

Reference Libraries

In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

Cytotoxicity of copper (II) oxide nanoparticles in rat and human intestinal cell models

In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response

Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures

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