Reference Libraries

December 11, 2015

ULTRASTRUCTURAL AND HISTOLOGICAL EFFECTS OF EXPOSURE TO CEES OR HEAT IN A HUMAN EPIDERMAL MODEL.

Ultrastructural and terminal deoxynucleotidyl transferase nick end labeling (TUNEL) studies were conducted to compare mechanisms of 2-chloroethyl ethyl sulfide (CEES) and heat-induced injury to EpiDerm™. Twenty-two hours after 2-h exposure to the mono-functional alkylating agent CEES, budding of cytoplasm, clumping... Read More

December 11, 2015

TOPICALLY APPLIED LIPOSOME-ENCAPSULATED T4 ENDONUCLEASE V INCREASES REPAIR OF UV-INDUCED CYCLOBUTANE PYRIMIDINE DIMERS IN NORMAL REPAIR PROFICIENT RECONSTRUCTED SKIN.

This study by scientists at AGI Dermatics demonstrated that MatTek’s EpiDermFT full-thickness in vitro human skin tissue equivalent can be used as a model for DNA repair in human skin and to investigate the effects of topical application of liposome-encapsulated... Read More

December 11, 2015

MATRIX METALLOPROTEINASE (MMP) EXPRESSION IN THE EPIDERM-FT SKIN EQUIVALENT: RELEVANCE TO DERMAL WOUND HEALING AND BLISTERING SKIN DISEASES.

Using MatTek’s EpiDermFT full-thickness in vitro human skin equivalent, scientists at MatTek Corp. showed that epidermal keratinocytes have a significant influence over the expression of matrix metalloproteinases (MMP’s) by dermal fibroblasts, demonstrating why EpiDermFT is useful in investigating MMP expression... Read More

December 11, 2015

TIMECOURSE OF HEALING AFTER UV-INDUCED DAMAGE IN THE EPIDERM-FT IN VITRO HUMAN SKIN MODEL.

Solar ultraviolet (UV) radiation is known to have deleterious effects on human skin. UVB (280-320 nm) and UVA (320-400 nm) segments of solar radiation have been shown to affect keratinocytes, the major cellular constituent of the epidermis, by causing direct... Read More

December 11, 2015

TO DEVELOP AN IN-VITRO (EFT-300) SKIN MODEL FOR THE STUDY OF WOUND HEALING.

This study by scientists at Florida A&M University College of Pharmacy and Pharmaceutical Sciences and MatTek Corp. demonstrated that MatTek’s EpiDermFT full-thickness in vitro human skin tissue equivalent is an excellent in vitro model for studying the human skin wound... Read More

Reference Libraries

ULTRASTRUCTURAL AND HISTOLOGICAL EFFECTS OF EXPOSURE TO CEES OR HEAT IN A HUMAN EPIDERMAL MODEL.

TOPICALLY APPLIED LIPOSOME-ENCAPSULATED T4 ENDONUCLEASE V INCREASES REPAIR OF UV-INDUCED CYCLOBUTANE PYRIMIDINE DIMERS IN NORMAL REPAIR PROFICIENT RECONSTRUCTED SKIN.

MATRIX METALLOPROTEINASE (MMP) EXPRESSION IN THE EPIDERM-FT SKIN EQUIVALENT: RELEVANCE TO DERMAL WOUND HEALING AND BLISTERING SKIN DISEASES.

TIMECOURSE OF HEALING AFTER UV-INDUCED DAMAGE IN THE EPIDERM-FT IN VITRO HUMAN SKIN MODEL.

TO DEVELOP AN IN-VITRO (EFT-300) SKIN MODEL FOR THE STUDY OF WOUND HEALING.

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