December 11, 2015
TIMECOURSE OF TH2 CYTOKINE-INDUCED GOBLET CELL HYPERPLASIA IN THE EPIAIRWAY™ IN VITRO HUMAN AIRWAY MODEL.
INTRODUCTION: Goblet cell hyperplasia and associated airway re-modeling contribute significantly to the pathogenesis of airway diseases such as asthma, rhinitis and COPD. TH2 cytokines including IL-4 and IL-13 are known to induce goblet cell hyperplasia in various in vivo animal... Read More