Reference Libraries

December 11, 2015

EPIDERM™ FULL THICKNESS (EPIDERM-FT™), A DERMAL-EPIDERMAL SKIN MODEL WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Paracrine signaling between dermal fibroblasts (FB) and epidermal keratinocytes (KC) is believed to modulate skin responses during contact irritant or allergic reactions. Dermal FB also play an important role in photo-aging and photo-damage, wound healing and cancer progression. To enable... Read More

December 11, 2015

WOUND HEALING RESPONSE OF THE EPIDERM FULL THICKNESS (EPIDERM-FT™) IN VITRO HUMAN SKIN EQUIVALENT AFTER SOLAR UV IRRADIATION: COMPARISON TO EXCISED HUMAN SKIN.

Normal human epidermal keratinocytes (KC) and dermal fibroblasts (FB) were cultured to produce full-thickness skin equivalents consisting of FB-containing dermal and stratified epidermal components with a fully developed basement membrane at the dermal/epidermal junction (EpiDerm-FT 200, EFT). The wound healing... Read More

December 11, 2015

Dermatophytes Activate Skin Keratinocytes via Mitogen-Activated Protein Kinase Signaling and Induce Immune Responses

Dermatophytes cause superficial and cutaneous fungal infections in immunocompetent hosts and invasive disease in immunocompromised hosts. However, the host mechanisms that regulate innate immune responses against these fungi are largely unknown. Here, we utilized commercially available epidermal tissues and primary... Read More

December 11, 2015

CUTANEOUS WOUND HEALING IN THE EPIDERMFT™ FULL-THICKNESS IN VITRO HUMAN SKIN MODEL: ROLE OF SERUM GROWTH FACTORS.

Timely and efficient epidermal wound healing is necessary for normal skin barrier function. Cutaneous wound healing involves interactions between dermal fibroblasts and epidermal keratinocytes as well as cell-extracellular matrix interactions (1-4). The current study describes wound healing experiments conducted in... Read More

December 11, 2015

BACTERIAL INACTIVATION OF WOUND INFECTION IN A HUMAN SKIN MODEL BY LIQUID-PHASE DISCHARGE PLASMA.

Background: We investigate disinfection of a reconstructed human skin model contaminated with biofilm-formative Staphylococcus aureus employing plasma discharge in liquid. Principal Findings: We observed statistically significant 3.83-log10 (p,0.001) and 1.59-log10 (p,0.05) decreases in colony forming units of adherent S. aureus... Read More

Reference Libraries

EPIDERM™ FULL THICKNESS (EPIDERM-FT™), A DERMAL-EPIDERMAL SKIN MODEL WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

WOUND HEALING RESPONSE OF THE EPIDERM FULL THICKNESS (EPIDERM-FT™) IN VITRO HUMAN SKIN EQUIVALENT AFTER SOLAR UV IRRADIATION: COMPARISON TO EXCISED HUMAN SKIN.

Dermatophytes Activate Skin Keratinocytes via Mitogen-Activated Protein Kinase Signaling and Induce Immune Responses

CUTANEOUS WOUND HEALING IN THE EPIDERMFT™ FULL-THICKNESS IN VITRO HUMAN SKIN MODEL: ROLE OF SERUM GROWTH FACTORS.

BACTERIAL INACTIVATION OF WOUND INFECTION IN A HUMAN SKIN MODEL BY LIQUID-PHASE DISCHARGE PLASMA.

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