December 11, 2015
Reference Libraries
December 11, 2015
POMEGRANATE DERIVED PRODUCTS FOR CANCER CHEMOPREVENTION.
This study by researchers in the University of Wisconsin’s Dept. of Dermatology used MatTek’s EpiDermFT full-thickness in vitro 3-D human skin tissue equivalent because it “sustains differentiation and exhibits morphological and metabolic properties similar to human skin”, to demonstrate the... Read More
December 11, 2015
FULL THICKNESS EPIDERM™, A DERMAL-EPIDERMAL SKIN MODEL TO STUDY EPITHELIAL-MESENCHYMAL INTERACTIONS.
It has long been recognized that significant paracrine signaling occurs between dermal fibroblasts and epidermal keratinocytes. Further, it is understood that such interactions likely modulate the response of skin to materials which may lead to contact irritant or allergic responses.... Read More
December 11, 2015
Wound healing revised: A novel reepithelialization mechanism revealed by in vitro and in silico models
Wound healing is a complex process in which a tissue’s individual cells have to be orchestrated in an efficient and robust way. We integrated multiplex protein analysis, immunohistochemical analysis, and whole-slide imaging into a novel medium-throughput platform for quantitatively capturing... Read More
December 11, 2015
WOUNDING UPREGULATES VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION BY KERATINOCYTES OF IN VITRO RECONSTRUCTED HUMAN EPIDERMIS.
Vascular endothelial growth factor (VEGF) is produced by keratinocytes and has been implicated in the past in animal models as the major factor involved in wound healing associated angiogenesis. In the present study we investigated the effects of wounding on... Read More