Reference Libraries

There is substantial interest in evaluating cosmetic raw materials for effects on melanin production. Since tyrosinase activity is considered rate limiting in melanogenesis, potential skin lightening materials are often screened by measuring their effects on this enzyme. However, melanogenesis involves... Read More

Organotypic skin models provide a useful, non-animal means to assess the irritancy and efficacy properties of various cosmetic products. To address the modulation of skin pigmentation, MatTek Corporation has developed MelanoDerm, a highly differentiated, three-dimensional tissue culture model of human... Read More