Reference Libraries

December 11, 2015

AN IN VITRO METHOD FOR SCREENING SKIN-WHITENING PRODUCTS.

Melanoderm™ (MatTek) is an in vitro model of the human epidermis consisting of well-differentiated, cultured human keratinocytes and melanocytes. We utilized this model to evaluate the efficacy, stability, and cytotoxicity of whitening agents. Magnesium ascorbyl phosphate (MAP), kojic acid and... Read More

December 11, 2015

NON-ANIMAL METHODS FOR TOXICITY TESTING: SKIN IRRITATION/CORROSION.

Skin toxicity refers to the local toxic effects resulting from a topical exposure of the skin to a substance. Skin toxicities include skin irritation and skin corrosion. The Globally Harmonized System of Classification and Labeling of Chemicals (GHS) defines skin... Read More

December 11, 2015

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

This study by scientists at Oxonica, Product Assessment & Regulatory Compliance, and SafePharm Laboratories Ltd. demonstrated that MatTek’s EpiDerm in vitro tissue model system can be used to determine the skin irritation potential of formulations containing nanoparticles. Nanotechnology is the... Read More

December 11, 2015

1-(2,4-DIHYDROXYPHENYL)-3-(2,4-DIMETHOXY-3-METHYL-PHENYL)PROPANE, A NOVEL TYROSINASE INHIBITOR WITH STRONG DEPIGMENTING EFFECTS.

This study by researchers at Unigen Pharmaceuticals and Texas Christian University demonstrated that MatTek’s MelanoDerm in vitro human skin tissue equivalent is an excellent in vitro model for studying the efficacy and safety of novel human skin lightening compounds. A... Read More

December 11, 2015

CONFOCAL MICROSCOPY FOR MODELING ELECTRON MICROBEAM IRRADIATION OF SKIN.

For radiation exposures employing targeted sources such as particle microbeams, the deposition of energy and dose will depend on the spatial heterogeneity of the sample. Although cell structural variations are rela- tively minor for two-dimensional cell cultures, they can vary... Read More

Reference Libraries

AN IN VITRO METHOD FOR SCREENING SKIN-WHITENING PRODUCTS.

NON-ANIMAL METHODS FOR TOXICITY TESTING: SKIN IRRITATION/CORROSION.

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

1-(2,4-DIHYDROXYPHENYL)-3-(2,4-DIMETHOXY-3-METHYL-PHENYL)PROPANE, A NOVEL TYROSINASE INHIBITOR WITH STRONG DEPIGMENTING EFFECTS.

CONFOCAL MICROSCOPY FOR MODELING ELECTRON MICROBEAM IRRADIATION OF SKIN.

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