Reference Libraries

December 11, 2015

EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.

This study by scientists at Florida A&M University College of Pharmacy, Auburn University Harrison School of Pharmacy, and MatTek Corp. demonstrated that MatTek’s EpiDerm in vitro human skin tissue equivalent is an excellent in vitro alternative to animal testing for... Read More

December 11, 2015

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

This study by scientists at Oxonica, Product Assessment & Regulatory Compliance, and SafePharm Laboratories Ltd. demonstrated that MatTek’s EpiDerm in vitro tissue model system can be used to determine the skin irritation potential of formulations containing nanoparticles. Nanotechnology is the... Read More

December 11, 2015

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

Psoriasis is a chronic condition characterized by formation of white scaly patches on the skin. Current treatment options include topical glucocorticoids which have several side effects. Pentaerythritol tetrakis (3,5-di-tert-butyl-4-hydroxyhydrocinnamate) (PTTC) is a cinnamate tetraester which may be used as a... Read More

December 11, 2015

NON-ANIMAL METHODS FOR TOXICITY TESTING: SKIN IRRITATION/CORROSION.

Skin toxicity refers to the local toxic effects resulting from a topical exposure of the skin to a substance. Skin toxicities include skin irritation and skin corrosion. The Globally Harmonized System of Classification and Labeling of Chemicals (GHS) defines skin... Read More

December 11, 2015

AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.

A great need exists in the cosmetics industry for in vitro screening methods that can provide accurate predictions of potential product or ingredient irritation. A variety of in vitro methods exist that utilize cell cultures, some of these focusing on... Read More

Reference Libraries

EVALUATION OF EPIDERM™ AS A MODEL TO STUDY IRRITATION AFTER EXPOSURE TO VARIOUS ALIPHATIC HYDROCARBONS FOUND IN JET FUELS.

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

NON-ANIMAL METHODS FOR TOXICITY TESTING: SKIN IRRITATION/CORROSION.

AN IN VITRO METHOD FOR SCREENING ANTI-IRRITANTS ON UV AND CHEMICALLY TREATED, RECONSTITUTED, THREE DIMENSIONAL HUMAN SKIN.

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