Reference Libraries

December 11, 2015

INHIBITORY EFFECTS OF Á-ARBUTIN ON MELANIN SYNTHESIS IN CULTURED HUMAN MELANOMA CELLS AND A THREE-DIMENSIONAL HUMAN SKIN MODEL.

We studied the inhibitory effects of 4-hydroxyphenyl á-glucopyranoside (á-arbutin) on melanogenesis in cultured human melanoma cells, HMV-II, and in a three-dimensional cultured human skin model. á-Arbutin showed no inhibitory effect on HMV-II cell growth at a concentration below 1.0 mM.... Read More

December 11, 2015

RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS.

Special Section. (See MatTek TR’s 276 thru 283.)

December 11, 2015

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

This study by scientists at Oxonica, Product Assessment & Regulatory Compliance, and SafePharm Laboratories Ltd. demonstrated that MatTek’s EpiDerm in vitro tissue model system can be used to determine the skin irritation potential of formulations containing nanoparticles. Nanotechnology is the... Read More

December 11, 2015

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

Cytokines important to the inflammatory cascade were measured both at the level of transcription and secreted protein, from skin equivalents topically exposed to a panel of relevant consumer products. The response of a full thickness model, consisting of both keratinocytes... Read More

December 11, 2015

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

Psoriasis is a chronic condition characterized by formation of white scaly patches on the skin. Current treatment options include topical glucocorticoids which have several side effects. Pentaerythritol tetrakis (3,5-di-tert-butyl-4-hydroxyhydrocinnamate) (PTTC) is a cinnamate tetraester which may be used as a... Read More

Reference Libraries

INHIBITORY EFFECTS OF Á-ARBUTIN ON MELANIN SYNTHESIS IN CULTURED HUMAN MELANOMA CELLS AND A THREE-DIMENSIONAL HUMAN SKIN MODEL.

RECONSTRUCTED HUMAN EPIDERMIS EQUIVALENTS.

INITIAL IN VITRO SCREENING APPROACH TO INVESTIGATE THE POTENTIAL HEALTH AND ENVIRONMENTAL HAZARDS OF ENVIROX™ – A NANOPARTICULATE CERIUM OXIDE DIESEL FUEL ADDITIVE.

DEVELOPMENT OF AN IN VITRO MODEL FOR THE PREDICTION OF SKIN IRRITATION POTENTIAL.

Skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis

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